Results 41 to 50 of about 2,834,111 (323)

Finite element simulation of barge impact into a rigid wall

open access: yesAlexandria Engineering Journal, 2014
The forces and locations of inland barge impacts currently control the design specifications for lock walls. This has resulted in a significant increase in the final construction costs of these walls.
H.W. Leheta   +2 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

On the Origins of Hamilton’s Principle(s)

open access: yesEncyclopedia
This entry first provides an overview of the historical, cultural and epistemological background that is key for Hamilton’s positions on mechanics. We consider the investigations on geometrical optics in the 17th and 18th centuries, Euler’s and Lagrange ...
Paolo Bussotti   +2 more
doaj   +1 more source

Classical analytical mechanics and entropy production [PDF]

open access: yesAmerican Journal of Physics, 2007
The usual canonical Hamiltonian or Lagrangian formalism of classical mechanics applied to macroscopic systems describes energy conserving adiabatic motion. If irreversible diabatic processes are to be included, the law of increasing entropy must also be considered. The notion of entropy then enters into the classical mechanical formalism. The resulting
Allan Widom, Jesse L. Silverberg
openaire   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Non-holonomic constraints: Considerations on the least action principle also from a thermodynamic viewpoint

open access: yesResults in Physics, 2023
For the system with non-holonomic constraints, the principle of least action does not seem to lead to the equations describing the motion, which are consistent with the physical behaviour. Here, some considerations are developed on this fundamental topic
Umberto Lucia, Giulia Grisolia
doaj  

Entropy regularized reinforcement learning using large deviation theory

open access: yesPhysical Review Research, 2023
Reinforcement learning (RL) is an important field of research in machine learning that is increasingly being applied to complex optimization problems in physics.
Argenis Arriojas   +3 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

A dinâmica de um elipsoide em rotação

open access: yesRevista Brasileira de Ensino de Física
Um fenômeno físico interessante que contraria nosso senso comum concerne à dinâmica do movimento de um elipsoide em rotação numa superfície não lisa. Um elipsoide em rotação é, por exemplo, um ovo cozido, girando numa mesa de superfície áspera.
Laysa G. Martins, José A.C. Nogales
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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