Results 91 to 100 of about 52,724 (260)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Modeling a healthcare system as a queueing network:The case of a Belgian hospital. [PDF]
The performance of health care systems in terms of patient flow times and utilization of critical resources can be assessed through queueing and simulation models.
Creemers, Stefan, Lambrecht, Marc
core
The Effects of JIT on the Development of Productivity Norms [PDF]
, 1997 Low inventory, or just-in-time (JIT) manufacturing systems, enjoy increasing application worldwide, yet the behavioral effects of such systems remain largely unexplored.
Boudreau, John W. +2 more
core +1 more source
A novel tool for organisational learning and its impact on safety culture in a hospital dispensary [PDF]
, 2012 Incident reporting as a key mechanism for organisational learning and the establishment of a stronger safety culture are pillars of the current patient safety movement.
Sujan, Mark-Alexander
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Design and performance of duct acoustic treatment [PDF]
, 1991 The procedure for designing acoustic treatment panels used to line the walls of aircraft engine ducts and for estimating the resulting suppression of turbofan engine duct noise is discussed.
Kraft, R. E., Motsinger, R. E.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
HIV Research & Clinical PracticeBackground HIV cure trials involving analytical treatment interruptions (ATIs) are expanding in resource-limited settings where HIV prevalence is highest, such as South Africa.
Maud Mthembu +6 more
doaj +1 more source
Mathematical modelling of internal HIV dynamics [PDF]
, 2009 We study a mathematical model for the viral dynamics of HIV in an infected individual in the presence of HAART. The paper starts with a literature review and then formulates the basic mathematical model.
Dalal, Nirav +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source