Results 81 to 90 of about 52,724 (260)

Exploring Barriers to Medication Safety in an Ethiopian Hospital Emergency Department: A Human Factors Engineering Approach

INNOVATIONS in Pharmacy, 2018
Objective: To describe challenges associated with the medication use process and potential medication safety hazards in an Ethiopian hospital emergency department using a human factors approach.
Ephrem Abebe, Michelle A. Chui
doaj   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Consensus communication strategies to improve doctor-patient relationship in paediatric severe asthma [PDF]

, 2019
Background: Asthma is a chronic inflammatory disease that is very common among youth worldwide. The burden of this illness is very high not only considering financial costs but also on emotional and social functioning.
Ahmad Kantar, Alessandro Giovanni Fiocchi, Alessandro Policreti, Anna Lucania, Antonietta Cappuccio, Elio Massimo Novembre, Emanuela di Palmo, Enrico Lombardi, Enza D’Auria, Filomena Bugliaro, Francesca Santamaria, Francesco Gesualdo, Gianluigi Marseglia, Giorgio Piacentini, Guido Pellegrini, Lucia Caminiti, Margherita Marchiani, Maria Carmela Montera, Maria Giulia Marini, Marzia Duse, on behalf of Paediatric Sound Group, Silvia Maria Elena Caimmi, Valeria Caldarelli   +22 more
core   +2 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Motivations, acceptability and ethical considerations for interventional HIV cure research at the end of life: perspectives from long-term survivors of HIV in the United States

BMC Medical Ethics
Introduction Despite progress in antiretroviral therapy (ART), an effective cure for HIV remains out of reach. End-of-life (EOL) research studies involving individuals with a prognosis of six months or less offers an opportunity to advance cure science ...
Ali Ahmed, Jeff Taylor, Whitney Tran, Simran Swaitch, Samuel O. Ndukwe, Rachel Lau, Kris H. Oliveira, Stephanie Solso, Cheryl Dullano, Andy Kaytes, Davey Smith, Robert Deiss, Sara Gianella, Karine Dubé   +13 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Optimal management of bio-based energy supply chains under parametric uncertainty through a data-driven decision-support framework [PDF]

, 2019
This paper addresses the optimal management of a multi-objective bio-based energy supply chain network subjected to multiple sources of uncertainty.
Espuña Camarasa, Antonio, Lupera Calahorrano, Gicela Jazmín, Medina González, Sergio Armando, Shokry Abdelaleem Taha Zied, Ahmed, Silvente Saiz, Javier   +4 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Definition of viroIogical endpoints improving the design of HIV cure strategies using analytical antiretroviral treatment interruption

Clinical Infectious Diseases
AbstractBackgroundAnalytical treatment interruption (ATI) is the gold standard in HIV research to validate the ability of novel therapeutic strategies to long-term control viremia without antiretroviral treatment (ART). Viral setpoint is commonly used as endpoint to evaluate their efficacy.
Alexandre, Marie, Prague, Mélanie, Lhomme, Edouard, Lelièvre, Jean-Daniel, Wittkop, Linda, Richert, Laura, Lévy, Yves, Thiébaut, Rodolphe   +7 more
openaire   +3 more sources