Results 91 to 100 of about 167,277 (315)
Advanced Science, EarlyView.This study uncovers a previously unknown crosstalk between two major ubiquitin ligases, CRL5 and APC/C. The authors identify APC11 as a binding partner of CUL5, showing that their interaction regulates neddylation, substrate stability, and mitotic progression.
Danrui Cui +10 more
wiley +1 more source
Meiotic behavior of small chromosomes in maize
Frontiers in Plant Science, 2013 The typical behavior of chromosomes in meiosis is that homologous pairs synapse, recombine and then separate at anaphase I. At anaphase II, sister chromatids separate.
James A. Birchler, Fangpu eHan
doaj +1 more source
Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]
, 1981 A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Altmann +34 more
core +2 more sources
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability
Journal of Cell Biology, 2014 TopBP1/Dpb11 prevents accumulation of anaphase chromatin bridges by stimulating the Mec1/ATR kinase and suppressing homologous recombination.
S. M. Germann +6 more
semanticscholar +1 more source
A theoretical model of anaphase
Mathematical BiosciencesThis paper develops a theory for anaphase in cells. After a brief description of microtubules, the mitotic spindle and the centrosome, a mathematical model for anaphase is introduced and developed in the context of the cell cytoplasm and liquid crystalline structures.
Brian D. Sleeman, Iain W. Stewart
openaire +3 more sources
The Anaphase-Promoting Complex/Cyclosome Is Required for Anaphase Progression in Multinucleated Ashbya gossypii Cells [PDF]
Eukaryotic Cell, 2007 ABSTRACT Regulated protein degradation is essential for eukaryotic cell cycle progression. The anaphase-promoting complex/cyclosome (APC/C) is responsible for the protein destruction required for the initiation of anaphase and the exit from mitosis, including the degradation of securin and B-type cyclins.
Gladfelter, A. S. +5 more
openaire +3 more sources
Nature Communications, 2020 Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei +3 more
doaj +1 more source
Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in Caenorhabditis elegans. [PDF]
PLoS Genetics, 2018 Chromosome congression and segregation in C. elegans oocytes depend on a complex of conserved proteins that forms a ring around the center of each bivalent during prometaphase; these complexes are then removed from chromosomes at anaphase onset and ...
Amanda C Davis-Roca +3 more
doaj +1 more source
Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast. [PDF]
, 2019 Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Chetlapalli, Keerthana +6 more
core +1 more source
The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase. [PDF]
, 2018 Smk1 is a meiosis-specific MAP kinase (MAPK) in budding yeast that is required for spore formation. It is localized to prospore membranes (PSMs), the structures that engulf haploid cells during meiosis II (MII).
Diamond, Aviva +5 more
core +3 more sources