Results 61 to 70 of about 66,778 (245)

Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in Caenorhabditis elegans. [PDF]

open access: yesPLoS Genetics, 2018
Chromosome congression and segregation in C. elegans oocytes depend on a complex of conserved proteins that forms a ring around the center of each bivalent during prometaphase; these complexes are then removed from chromosomes at anaphase onset and ...
Amanda C Davis-Roca   +3 more
doaj   +1 more source

The Anaphase-Promoting Complex [PDF]

open access: yesMolecular Cell, 2002
Key events in mitosis such as sister chromatid separation and subsequent inactivation of cyclin-dependent kinase 1 are regulated by ubiquitin-dependent proteolysis. These events are mediated by the anaphase-promoting complex (APC), a cell cycle-regulated ubiquitin ligase that assembles multiubiquitin chains on regulatory proteins such as securin and ...
openaire   +3 more sources

Interaction Between Actin and Microtubules During Plant Development

open access: yesCytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu   +3 more
wiley   +1 more source

Chiasmata promote monopolar attachment of sister chromatids and their co-segregation toward the proper pole during meiosis I. [PDF]

open access: yesPLoS Genetics, 2011
The chiasma is a structure that forms between a pair of homologous chromosomes by crossover recombination and physically links the homologous chromosomes during meiosis. Chiasmata are essential for the attachment of the homologous chromosomes to opposite
Yukinobu Hirose   +8 more
doaj   +1 more source

Cell Division: SACing the Anaphase Problem [PDF]

open access: yesCurrent Biology, 2014
Errors in chromosome segregation are safeguarded by the spindle assembly checkpoint. Yet the very defects that trigger this checkpoint are inescapable consequences of sister chromatid segregation in anaphase. Three new studies provide clues to how cells cope with this problem.
openaire   +3 more sources

On the origins of ultra-fine anaphase bridges [PDF]

open access: yesCell Cycle, 2009
Comment on: Chan KL, Palmai-Pallag T, Ying S, Hickson ID. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat Cell Biol 2009; 11:753-60.
Kok-Lung Chan, Ian D. Hickson
openaire   +2 more sources

Mechanical Coupling With the Nuclear Envelope Shapes the Schizosaccharomyces pombe Mitotic Spindle

open access: yesCytoskeleton, EarlyView.
ABSTRACT The fission yeast Schizosaccharomyces pombe divides via closed mitosis, meaning that spindle elongation and chromosome segregation transpire entirely within the closed nuclear envelope. Both the spindle and nuclear envelope must undergo shape changes and exert varying forces on each other during this process.
Marcus A. Begley   +8 more
wiley   +1 more source

Air-drying of cells enables visualization of antiparallel microtubule overlaps in the spindle midzone

open access: yesMethodsX, 2018
Immunofluorescence staining is used extensively to examine various types of cellular events. However, even when an antibody can detect its epitopes in western blotting, it sometimes fails to detect its epitopes when used for immunofluorescence staining ...
Aya Ifuji, Takahisa Kuga, Yuji Nakayama
doaj   +1 more source

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

open access: yesNature Communications, 2020
Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei   +3 more
doaj   +1 more source

The FEAR protein Slk19 restricts Cdc14 phosphatase to the nucleus until the end of anaphase, regulating its participation in mitotic exit in Saccharomyces cerevisiae. [PDF]

open access: yesPLoS ONE, 2013
In Saccharomyces cerevisiae mitosis, the protein Slk19 plays an important role in the initial release of Cdc14 phosphatase from the nucleolus to the nucleus in early anaphase, an event that is critical for proper anaphase progression. A role for Slk19 in
Ann Marie E Faust   +4 more
doaj   +1 more source

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