Results 91 to 100 of about 7,925 (224)

Macrophage Matrix Metalloproteinase-12 Dampens Inflammation and Neutrophil Influx in Arthritis

open access: yesCell Reports, 2014
Resolution of inflammation reduces pathological tissue destruction and restores tissue homeostasis. Here, we used a proteomic protease substrate discovery approach, terminal amine isotopic labeling of substrates (TAILS), to analyze the role of the ...
Caroline L. Bellac   +13 more
doaj   +1 more source

Alloantibody Generation and Effector Function Following Sensitization To Human Leukocyte Antigen

open access: yesFrontiers in Immunology, 2016
Allorecognition is the activation of the adaptive immune system to foreign Human Leukocyte Antigen (HLA) resulting in the generation of alloantibodies.
Michelle J Hickey   +2 more
doaj   +1 more source

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

open access: yes, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

Complement-dependent neuroinflammation in spinal cord injury: from pathology to therapeutic implications

open access: yesNeural Regeneration Research
Spinal cord injury remains a major cause of disability in young adults, and beyond acute decompression and rehabilitation, there are no pharmacological treatments to limit the progression of injury and optimize recovery in this population.
Hassan Saad   +12 more
doaj   +1 more source

C4a: An Anaphylatoxin in Name Only [PDF]

open access: yesJournal of Innate Immunity, 2015
Activation of complement leads to generation of the 3 anaphylatoxins C3a, C4a, and C5a. Although all 3 peptides are structurally similar, only C3a and C5a share a similar functional profile that includes the classic inflammatory activities and, more recently, developmental homing and regenerative properties among others.
openaire   +2 more sources

FACTORS OF THE ACUTE PHASE OF INFLAMMATION AS MODULATORS OF THE INTERACTION OF MAST CELLS AND FIBROBLASTS

open access: yesActa Biomedica Scientifica, 2012
We investigated the influence of factors of the acute phase of inflammation (purified anaphylatoxins C3a and C5a, pentraxin C-reactive protein (CRP), and aggregated. IgG (aIgG) — as an analogue of circulating immune complexes) on the adhesive interaction
S. A. Trulioff   +2 more
doaj  

Indoor microbial exposure increases complement component C3a and C-reactive protein concentrations in serum

open access: yesHeliyon
Indoor exposure to microbial growth, caused by moisture damage, has been an established health risk for several decades. It is likely that a damp indoor environment contains biological pollutants that trigger both the innate and adaptive branches of the ...
Outi Karhuvaara   +4 more
doaj   +1 more source

ANAPHYLATOXIN AND ANAPHYLAXIS

open access: yesJournal of the American Medical Association, 1917
It is our purpose to summarize the results of investigations which are published concurrently, under the same general heading, as a series of ten articles in the May and June numbers of the Journal of Infectious Diseases . For details, the reader must consult the experimental work there given.
openaire   +2 more sources

THE NATURE OF ANAPHYLATOXIN [PDF]

open access: yesJournal of Experimental Medicine, 1915
1. The union of fresh serum of pregnant or immunized animals with the corresponding boiled protein (substratum) is accompanied by the formation of poisonous substances. 2. The poison originates from the serum as a result of its autodigestion, and not from the substratum. 3. The process of autodigestion may be determined by
openaire   +1 more source

anaphylatoxin

open access: yes
Citation: 'anaphylatoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12873 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +1 more source

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