Results 71 to 80 of about 5,613 (194)

Regulation of Human Mast Cell and Basophil Function by Anaphylatoxins C3a and C5a [PDF]

, 2010
Allergic diseases such as asthma result from inappropriate immunologic responses to common environmental allergens in genetically susceptible individuals.
Ali, Hydar
core   +1 more source

Human serum anaphylatoxins generation induced by Ps82.

, 2015
Samples of NHS (50 μL) were incubated with Ps82 (0.33 μg/mL) or the Premolis semirufa’s bristles extract (175 μg/mL), in the presence or absence of 10 mM 1,10-Phenanthroline (Phen), for 30 min at 37°C.
Rute M. Gonçalves-de-Andrade (449319), Denise V. Tambourgi (53063), Carmen W. van den Berg (331097), Isadora Maria Villas Boas (701026), Fabio Carlos Magnoli (5662393), Giselle Pidde-Queiroz (331095)   +5 more
core   +1 more source

Acidosis activates complement system in vitro

Mediators of Inflammation, 1998
We investigated the in vitro effect of different form s of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 μ mol/ml blood) or lactic acid (5.5 μ mol/ml) to heparin blood (N=12)
Michael Emeis, Josef Sonntag, Carsten Willam, Evelyn Strauss, Matthias M. Walka, Michael Obladen   +5 more
doaj   +1 more source

Complement in Kidney Transplantation

Frontiers in Medicine, 2017
The complement system is considered to be an important part of innate immune system with a significant role in inflammation processes. The activation can occur through classical, alternative, or lectin pathway, resulting in the creation of anaphylatoxins
Marek Cernoch, Ondrej Viklicky, Ondrej Viklicky   +2 more
doaj   +1 more source

Involvement of anaphylatoxins and their corresponding receptors in cartilage calcifcation during osteoarthritis progression

Within this thesis, I investigated the role of the complement system in osteoarthritis (OA) progression. I focused mainly on the anaphylatoxins C3a and C5a and their respective receptors C3aR and C5aR1 and whether they are involved in cartilage ...
Ruths, Leonie
core   +1 more source

Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization

International Journal of Nanomedicine, 2018
Tamás Mészáros,1,2,* Gergely Tibor Kozma,2,* Taro Shimizu,3 Koga Miyahara,3 Keren Turjeman,4 Tatsuhiro Ishida,3 Yechezkel Barenholz,4 Rudolf Urbanics,1,2 János Szebeni1,2,5 1Nanomedicine Research and Education Center ...
Mészáros T, Kozma GT, Shimizu T, Miyahara K, Turjeman K, Ishida T, Barenholz Y, Urbanics R, Szebeni J   +8 more
doaj  

Macrophage Matrix Metalloproteinase-12 Dampens Inflammation and Neutrophil Influx in Arthritis

Cell Reports, 2014
Resolution of inflammation reduces pathological tissue destruction and restores tissue homeostasis. Here, we used a proteomic protease substrate discovery approach, terminal amine isotopic labeling of substrates (TAILS), to analyze the role of the ...
Caroline L. Bellac, Antoine Dufour, Michael J. Krisinger, Anantasak Loonchanta, Amanda E. Starr, Ulrich auf dem Keller, Philipp F. Lange, Verena Goebeler, Reinhild Kappelhoff, Georgina S. Butler, Leslie D. Burtnick, Edward M. Conway, Clive R. Roberts, Christopher M. Overall   +13 more
doaj   +1 more source

Alloantibody Generation and Effector Function Following Sensitization To Human Leukocyte Antigen

Frontiers in Immunology, 2016
Allorecognition is the activation of the adaptive immune system to foreign Human Leukocyte Antigen (HLA) resulting in the generation of alloantibodies.
Michelle J Hickey, Nicole M Valenzuela, Elaine F Reed   +2 more
doaj   +1 more source

Complement-dependent neuroinflammation in spinal cord injury: from pathology to therapeutic implications

Neural Regeneration Research
Spinal cord injury remains a major cause of disability in young adults, and beyond acute decompression and rehabilitation, there are no pharmacological treatments to limit the progression of injury and optimize recovery in this population.
Hassan Saad, Bachar El Baba, Ali Tfaily, Firas Kobeissy, Juanmarco Gutierrez Gonzalez, Daniel Refai, Gerald R. Rodts, Christian Mustroph, David Gimbel, Jonathan Grossberg, Daniel L. Barrow, Matthew F. Gary, Ali M. Alawieh   +12 more
doaj   +1 more source

FACTORS OF THE ACUTE PHASE OF INFLAMMATION AS MODULATORS OF THE INTERACTION OF MAST CELLS AND FIBROBLASTS

Acta Biomedica Scientifica, 2012
We investigated the influence of factors of the acute phase of inflammation (purified anaphylatoxins C3a and C5a, pentraxin C-reactive protein (CRP), and aggregated. IgG (aIgG) — as an analogue of circulating immune complexes) on the adhesive interaction
S. A. Trulioff, I. V. Kudryavtsev, P. G. Nazarov   +2 more
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