Results 11 to 20 of about 1,268 (131)

The 'Health Collapse Spiral': A 35-Month Longitudinal Case Study of Physiological Reserve Depletion in a Centenarian Following COVID-19. [PDF]

Clin Case Rep
ABSTRACT This 35‐month case report documents irreversible physiological reserve depletion in a centenarian multimorbid man after COVID‐19. Prior to infection, he maintained precarious homeostasis for 17 years despite severe frailty (CFS 7), with stable CKD stage 3a (eGFR 58.3 mL/min/1.73 m2) and albumin 36.2 g/L.
Xu S, Zhang W, Yin Q, Wei J, Ma Y, Jia W.   +5 more
europepmc   +2 more sources

Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study [PDF]

Gut Pathogens
Background Colistin resistance significantly constrains available treatment options and results in the emergence of pandrug-resistant (PDR) strains. Treating PDR infections is a major public health issue. A promising solution lies in using colistin-based
Eriny T. Attalla, Amal M. Khalil, Azza S. Zakaria, Rhiannon Evans, Nesrin S. Tolba, Nelly M. Mohamed   +5 more
doaj   +2 more sources

Editorial for the Special Issue: “Epidemiology, Prognosis and Antimicrobial Treatment of Extensively Antibiotic-Resistant Bacterial Infections”

Antibiotics, 2022
The increasing consumption of broad-spectrum antimicrobials is fuelling a vicious cycle leading to extensively drug-resistant (XDR) and pandrug-resistant (PDR) bacteria [...]
Stamatis Karakonstantis, Evangelos I. Kritsotakis   +1 more
doaj   +1 more source

Emergence of ST63 Pandrug-Resistant Acinetobacter pittii Isolated From an AECOPD Patient in China

Frontiers in Cellular and Infection Microbiology, 2021
Acinetobacter sp. is among the ESKAPE organisms which represent the major nosocomial pathogens that exhibited a high resistance rate. A. pittii, frequently associated with antimicrobial resistance particularly to carbapenems, is one of the most common ...
Ling Yang, Ning Dong, Chen Xu, Chen Xu, Lianwei Ye, Sheng Chen   +5 more
doaj   +1 more source

Increasing antimicrobial resistance in nosocomial pathogens; multidrug-resistant extensively drug-resistant and pandrug-resistant Acinetobacter baumannii [PDF]

Journal of Microbiology and Infectious Diseases, 2014
Objective: The aim of this study was to determine the antimicrobial susceptibility of Acinetobacter baumannii strains, which were isolated from nosocomial infections and compare the changes in resistance rates of isolates over time.Methods: Acinetobacter
Cem Celik, Mustafa Gokhan Gozel, Fatma Dayı, Mustafa Zahir Bakıcı, Nazif Elaldı, Esra Gulturk   +5 more
doaj   +2 more sources

Evaluation of blaGES-5 and bla veb-1 genes with multidrug-resistant extend, pandrug resistance patterns (MDR, XDR, PDR), and biofilm formation in Pseudomonas aeruginosa isolates

Cellular and Molecular Biology, 2021
Pseudomonas aeruginosa is a ubiquitous microorganism that is difficult to treat due to the increasing prevalence of multidrug resistance patterns. A total of 227 samples were taken from different clinical samples during the study period from January 2018 to December 2018. The isolates were identified with antibiotic sensitivity testing with ESBL by the
Fattma A, Ali, Sevan Hassan, Bakir, Sayran Hamed, Haji, Bashdar M, Hussen   +3 more
openaire   +3 more sources

High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be overcome by colistin-EDTA combination therapy

Scientific Reports, 2022
The global prevalence of colistin-resistant Klebsiella pneumoniae (ColRkp) facilitated by chromosomal and plasmid-mediated Ara4N or PEtN-remodeled LPS alterations has steadily increased with increased colistin usage for treating carbapenem-resistant K ...
Aye Mya Sithu Shein, Dhammika Leshan Wannigama, Paul G. Higgins, Cameron Hurst, Shuichi Abe, Parichart Hongsing, Naphat Chantaravisoot, Thammakorn Saethang, Sirirat Luk-in, Tingting Liao, Sumanee Nilgate, Ubolrat Rirerm, Naris Kueakulpattana, Sukrit Srisakul, Apichaya Aryukarn, Matchima Laowansiri, Lee Yin Hao, Manta Yonpiam, Naveen Kumar Devanga Ragupathi, Teerasit Techawiwattanaboon, Natharin Ngamwongsatit, Mohan Amarasiri, Puey Ounjai, Rosalyn Kupwiwat, Phatthranit Phattharapornjaroen, Vishnu Nayak Badavath, Asada Leelahavanichkul, Anthony Kicic, Tanittha Chatsuwan   +28 more
doaj   +1 more source

Mortality of Pandrug-Resistant Klebsiella pneumoniae Bloodstream Infections in Critically Ill Patients: A Retrospective Cohort of 115 Episodes

Antibiotics, 2021
Background: The increased frequency of bacteraemias caused by pandrug-resistant Klebsiella pneumoniae (PDR-Kp) has significant implications. The aim of the present study was to identify predictors associated with mortality of PDR-Kp bacteraemias. Methods:
Matthaios Papadimitriou-Olivgeris, Christina Bartzavali, Alexandra Georgakopoulou, Fevronia Kolonitsiou, Chrisavgi Papamichail, Iris Spiliopoulou, Myrto Christofidou, Fotini Fligou, Markos Marangos   +8 more
doaj   +1 more source

Incidence and Antibiotic Susceptibility of Gram-Negative Bacteria Associated With Chest Infections in Intensive Care Unit Patients From a Selected Hospital in the Kingdom of Saudi Arabia. [PDF]

Biomed Res Int
Background Hospital‐acquired pneumonia (HAP), including ventilator‐associated pneumonia (VAP), is a leading cause of morbidity and mortality in intensive care units (ICUs). Local, organism‐specific antimicrobial resistance data are critical to guide empiric therapy and strengthen antimicrobial stewardship efforts.
Almouwlid A, Albenasy K, Kamel Y, Abdelmoktader A, Alaidarous M, Abdel-Hadi A.   +5 more
europepmc   +2 more sources

Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina [PDF]

Medicinski Glasnik, 2015
Aim Recently increased attention and interest for Acinetobacterbaumannii are the result of the occurrence of multidrug resistant (MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world.
Amela Dedeić-Ljubović, Ðana Granov, Mirsada Hukić   +2 more
doaj   +1 more source