Results 161 to 170 of about 389,574 (340)
Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging
Food Safety and Health, EarlyView.This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout +3 more
wiley +1 more source
Screening anticancer peptides performance in organotypic prostate tumor‐stroma 3D models
International Journal of Cancer, EarlyView.What's New? Peptide‐based drugs have emerged as promising anticancer therapies for their potential to disrupt protein–protein interactions. In this study, the authors developed a physiomimetic human 3D prostate cancer spheroid model to assess the efficacy of the CAVPENET peptide in inhibiting tumor growth. Upon incubation with CAVPENET, prostate cancer
Bárbara Matos +7 more
wiley +1 more source
Neonatal Lung Diseases: A Clinical Potential for Sex Steroids and a Novel Intracrine Organ
Frontiers in Medicine, 2021 Yves Tremblay +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Micro‐and nanoplastics (MNPs) are breakdown products of plastics, and humans are exposed to these particles through air, water, food, and soil. There is a growing concern that human exposure to MNPs negatively impacts health. In this review we will discuss the potential health impact of MNPs on ovarian function and the hypothalamic–pituitary ...
Sanchayana Raghuvir +2 more
wiley +1 more source
MP62-14 ACTIVATION OF ABERRANT ANDROGEN RECEPTOR SIGNALING IN CARCINOMA ASSOCIATED FIBROBLASTS INDUCES PROSTATE CANCER PROGRESSION [PDF]
, 2016 Omar E. Franco +4 more
openalex +1 more source
iNew Medicine, EarlyView.ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi +14 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang +6 more
wiley +1 more source
Impact of organic pollutants on phenotype and gene expression in human breast cancer cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin +7 more
wiley +1 more source
A lex naturalis delineates components of a human-specific, adrenal androgen-dependent, p53-mediated ‘kill switch’ tumor suppression mechanism [PDF]
, 2020 Jonathan W. Nyce
openalex +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt +5 more
wiley +1 more source