Results 161 to 170 of about 378,224 (340)

Arrhythmic expression signatures of circadian clock‐associated transcription factors and chronic circadian disruption contribute to advanced prostate cancer growth

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Circadian rhythm disruption potentially fuels prostate cancer progression. The mechanisms and signaling molecules contributing to hormonal tumorigenesis, however, remain largely undefined. In this study, circadian expression patterns of core‐circadian controlled genes (CCCGs) and nuclear receptors (NRs) were investigated in advanced ...
Ria Chopra   +4 more
wiley   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Elevating and empowering reproductive futures: Pediatric and adolescent gynecology's specialized care across the globe

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pediatric and adolescent gynecology (PAG) is an expanding subspecialty of obstetrics and gynecology that addresses the reproductive health needs of girls and young women worldwide. In regions with limited subspecialist healthcare providers, general obstetricians, gynecologists, and nurse‐midwives, frontline healthcare providers provide ...
Nichole A. Tyson   +6 more
wiley   +1 more source

Gynecologic surgery for benign disease: Preserving reproductive potential

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preserving fertility is essential when managing benign gynecologic disorders in reproductive‐aged women. Surgical interventions can impact future fertility, therefore requiring an evidence‐based, individualized approach. The FIGO Committee on Reproductive Endocrinology and Infertility reviewed current literature to develop recommendations for ...
Togas Tulandi   +23 more
wiley   +1 more source

FIGO committee opinion: Environmental drivers of gynecologic and reproductive health

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract This FIGO committee opinion paper addresses the growing body of evidence linking environmental exposures to common gynecologic and reproductive conditions across the life course. From adolescence through menopause, women are exposed to a wide range of environmental toxicants, including endocrine‐disrupting chemicals, air pollutants, heavy ...
Nathaniel DeNicola   +9 more
wiley   +1 more source

FIGO committee opinion: Environmental drivers of obstetric health and early childhood development

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Environmental exposures are increasingly recognized as critical, yet underappreciated, determinants of reproductive, perinatal, and early childhood health. Developed through a structured consensus process and grounded in systematic evidence review, this FIGO committee opinion provides a comprehensive synthesis of the current evidence linking ...
Nathaniel DeNicola   +12 more
wiley   +1 more source

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