Results 21 to 30 of about 175,765 (268)

Divergent Associations Between Serum Androgens and Ovarian Reserve Markers Revealed in Patients With Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2022
BackgroundThe role of excess androgen in ovarian reserve remains unclear in patients with polycystic ovary syndrome (PCOS). Our study highlights the associations of serum androgen levels and ovarian reserve markers in PCOS and non-PCOS women ...
Youran Li, Youran Li, Yanhong Zhai, Yanhong Zhai, Lin Li, Yifan Lu, Yifan Lu, Shaofei Su, Ying Liu, Ying Liu, Zhengwen Xu, Zhengwen Xu, Mingwei Xin, Qiaoli Zhang, Zheng Cao, Zheng Cao   +15 more
doaj   +1 more source

Androgen Receptor and Mechanism of Androgen Action

Annals of Medicine, 1993
Androgen receptor is the intracellular protein that mediates biological actions of physiological androgens (testosterone and 5 alpha-dihydrotestosterone). Androgen receptor belongs to a large family of ligand-dependent proteins whose function is to modulate expression of genes and gene networks in a cell- and tissue-specific manner.
O A, Jänne, J J, Palvimo, P, Kallio, M, Mehto   +3 more
openaire   +2 more sources

Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus

Frontiers in Endocrinology, 2022
BackgroundThe associations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) with diabetic kidney disease (DKD) remained unclear. Thus, this cross-sectional study aimed to explore the associations of DHEA and DHEAS with the risk
Xinxin Zhang, Jinfeng Xiao, Xin Li, Jingqiu Cui, Kunling Wang, Qing He, Ming Liu, Ming Liu, Ming Liu   +8 more
doaj   +1 more source

Factors that influence the androgen receptor cistrome in benign and malignant prostate cells

Molecular Oncology, 2019
The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead ...
Ben T. Copeland, Juan Du, Sumanta K. Pal, Jeremy O. Jones   +3 more
doaj   +1 more source

Contextual modulation of social and endocrine correlates of fitness: insights from the life history of a sex changing fish

Frontiers in Neuroscience, 2015
Steroid hormones are critical regulators of reproductive life history, and the steroid sensitive traits (morphology, behavior, physiology) associated with particular life history stages can have substantial fitness consequences for an organism. Hormones,
Devaleena S Pradhan, Devaleena S Pradhan, Tessa K Solomon-Lane, Matthew Scott Grober, Matthew Scott Grober   +4 more
doaj   +1 more source

Neurology of Androgens and Androgenic Supplements

Current Neurology and Neuroscience Reports
Abstract Purpose of Review This article explores the intricate relationship between androgens, androgen receptors, and the central nervous system. We examine the role of physiologically derived androgens and androgenic supplements in neurodevelopment and neuroplasticity and delve into the involvement of androgen ...
Dengri, Chetna, Mayberry, Whitney, Koriesh, Ahmed, Nouh, Amre   +3 more
openaire   +2 more sources

Sex hormone-specific regulation of ferroptosis in vascular cells in atherosclerosis: molecular mechanisms and targeted strategies

Frontiers in Physiology
Atherosclerosis (AS), the leading cause of cardiovascular morbidity and mortality worldwide, exhibits significant sex differences in its incidence and pathological progression, yet the underlying molecular mechanisms remain fully elucidated. Ferroptosis,
Keying Yu, Keying Yu, Keying Yu, Jitong Li, Jitong Li, Tenghui Tian, Tenghui Tian, Rui Shi, Rui Shi, Yue Deng, Yue Deng, Yue Deng, Liping Chang, Liping Chang   +13 more
doaj   +1 more source

Regional variations and socioeconomic factors influencing sex hormone profiles in adolescent girls in Ghana

Frontiers in Reproductive Health
IntroductionAdolescence is a critical period of hormonal changes that affect growth, development, and behaviour. Estrogen, progesterone, and androgen are sex hormones that play important roles in reproductive development and functions.
Eric Kyei-Baafour, Sawudatu Zakariah-Akoto, Michael Ofori, Lutherodt Bentum-Ennin, Oscar Nii Otto Darko, Godfred Egbi, Benjamin Abuaku, Collins Ahorlu, Dorothy Yeboah-Manu   +8 more
doaj   +1 more source

The unique interplay of mitochondrial oxidative phosphorylation (OXPHOS) and immunity and its potential implication for the sex‐ and age‐related morbidity of severe COVID‐19 patients

MedComm, 2023
Aged male patients are more vulnerable to severe or critical symptoms of COVID‐19, but the underlying mechanism remains elusive. In this study, we analyzed previously published scRNA‐seq data from a large cohort of COVID‐19 patients, castrated and ...
Yinchuan Li, Lei Li, Guanghao Wu, Gangcai Xie, Lirong Yi, Jie Zhu, ShiYu Liang, Ya‐ru Huang, Juan Chen, Shaoyang Ji, Fei Sun, Rui‐tian Liu   +11 more
doaj   +1 more source

Parasite-Mediated Mate Preferences in a Cooperatively Breeding Rodent

Frontiers in Ecology and Evolution, 2022
Females of many species discriminate among males when choosing a mate and this can bear indirect and direct benefits including the avoidance of parasite transmission from infested males.
Heike Lutermann, Kemba B. Butler, Nigel C. Bennett   +2 more
doaj   +1 more source