Results 21 to 30 of about 333,981 (315)

Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]

, 1992
Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Fittler, Friedrich, Schulz, Peter, Wolf, Dieter A.   +2 more
core   +1 more source

Testosterone Acts Within the Medial Amygdala of Rats to Reduce Innate Fear to Predator Odor Akin to the Effects of Toxoplasma gondii Infection

Frontiers in Psychiatry, 2020
Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh, Shantala Arundathi Hari Dass, Samira Abdulai-Saiku, Ajai Vyas   +3 more
doaj   +1 more source

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics [PDF]

, 2009
Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures.
A de la Taille, A Glinka, A van Bokhoven, AA George, AP Verhagen, AS Waller, AT Collins, AT Collins, AT Collins, B Hoang, B Mao, BA Reynolds, C Lo Celso, C Wissmann, CC Carson 3rd, CI Truica, CL Hall, CL Hall, D Beier, D Bonnet, D Masiello, D Mizrak, DA Lawson, David M Prowse, DK Singla, DL Hudson, DL Hudson, DP Petrylak, DR Chesire, EM Hurt, G Dontu, G Gu, G Shaw, G Shaw, GD Richardson, GJ van Leenders, GL Shaw, GN Thalmann, H Clevers, H Li, H Zhu, HF English, Isabelle Bisson, IV Litvinov, IV Litvinov, J Miki, JA Schalken, JE Visvader, JM Adams, KD Bunting, KG Leong, L Adam, L Patrawala, L Patrawala, L Patrawala, L Ricci-Vitiani, L Vezzoni, L Xin, L Xin, LE Pascal, LG Wang, M Al-Hajj, M Locke, M Verras, MJ Linja, MS Chen, MS Wicha, N Uchida, PN Kelly, RI Bhatt, S Signoretti, S Weiss, S Zhou, SI Hwang, SK Singh, SM Janes, SV Shmelkov, T Hara, T Nikolova, T Reya, WJ Huss, Y Katoh, Y Lu   +82 more
core   +1 more source

The effect of different types of hepatic injury on the estrogen and androgen receptor activity of liver [PDF]

, 1989
Mammalian liver contains receptors for both estrogens and androgens. Hepatic regeneration after partial hepatectomy in male rats is associated with a loss of certain male-specific hepatic characteristics.
Aten R. F., Bannister P., Bardin C. W., Booth A. N., Cardon S. B., Chamness G. C., D. H. Van Thiel, D. Kahn, Eagon P. K., Eisenfeld A. J., Farrell G. C., Francavilla A., Francavilla A., Gustafsson J. A., H. Lai, Higgins E. M., L. Makowka, Lowry O. H., M. Kajani, P. K. Eagon, Q. Zeng, Starzl T. E., T. E. Starzl, Van DH Thiel, Van DH Thiel   +24 more
core   +1 more source

Canalization of the Vestibular Plate in the Absence of Urethral Fusion Characterizes Development of the Human Clitoris: The Single Zipper Hypothesis. [PDF]

, 2016
PurposeWe characterized the early gestation development of the female external genitalia using optical projection tomography to visualize anatomical structures at high resolution.Materials and methodsFirst and early second trimester human female fetal ...
Baskin, Laurence, Botta, Sisir, Cao, Mei, Cunha, Gerald, Li, Yi, Overland, Maya, Shen, Joel, Sinclair, Adriane, Yue, Xuan   +8 more
core   +2 more sources

Behavioral analysis of genetically modified mice indicates essential roles of neurosteroidal estrogen

Frontiers in Endocrinology, 2011
Brain aromatase is expressed only in the nerve cells of specific brain regions with a transient peak at the neonatal period when sexual behaviors become organized. Aromatase knockout (ArKO) mouse, generated to give light on the physiological functions of
Nobuhiro eHarada, Toru eWakatsuki, Shin-ichiro eHonda   +2 more
doaj   +1 more source

Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications

Frontiers in Oncology, 2023
Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential responses have been observed by sex, where men appear to respond better than women.
Vianey Rodriguez-Lara, Giovanny Soca-Chafre, Maria Rosa Avila-Costa, Juan Jose Juarez-Vignon Whaley, Jeronimo Rafael Rodriguez-Cid, José Luis Ordoñez-Librado, Emma Rodriguez-Maldonado, Nallely A. Heredia-Jara   +7 more
doaj   +1 more source

An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells [PDF]

, 2015
Funding: This work was supported by the Chief Scientist’s Office (CSO) of the Scottish Government (http://www.cso.scot.nhs.uk/): CWH (CZB-4-477) and IH (ETM/382).Peer reviewedPublisher ...
Hay, Colin W, Hunter, Irene, MacKenzie, Alasdair, McEwan, Iain J   +3 more
core   +3 more sources

Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]

, 1989
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla, A Mode, A Schleusener, AE Pegg, AJ Syms, B Katchen, CL Mendenhall, CW Bardin, D Kahn, DM Cohen, E Bresnidk, E Mezey, E Mezey, E Mezey, EM Higgins, ER Lax, F Neumann, J Simard, J Terblanche, JA Gustafsson, JA Gustafsson, JA McGowan, JH Clark, JM Kissane, JP Blondeau, KE Crow, LE Porter, M Kayfman, M Sarff, MF Zuretti, OH Lowry, PK Eagon, PK Eagon, PK Eagon, R Neri, W Welshons, WJ King   +36 more
core   +1 more source

Mitogen Activated Protein kinase signal transduction pathways in the prostate

Cell Communication and Signaling, 2004
The biochemistry of the mitogen activated protein kinases ERK, JNK, and p38 have been studied in prostate physiology in an attempt to elucidate novel mechanisms and pathways for the treatment of prostatic disease.
Koul Sweaty, Maroni Paul D, Meacham Randall B, Koul Hari K   +3 more
doaj   +1 more source