Results 41 to 50 of about 247,609 (252)

Androgen levels in autism spectrum disorders: a systematic review and meta-analysis

open access: yesFrontiers in Endocrinology
BackgroundAccumulating evidence suggests that the autism spectrum disorder (ASD) population exhibits altered hormone levels, including androgens. However, studies on the regulation of androgens, such as testosterone and dehydroepiandrosterone (DHEA), in ...
Zhao Wang   +14 more
doaj   +1 more source

Effects of oral contraceptives on spatial cognition depend on pharmacological properties and phase of the contraceptive cycle

open access: yesFrontiers in Endocrinology, 2022
The central nervous system effects of oral contraceptives (OCs) are not well-documented. In a set of 3 studies, we investigated a specific cognitive function, mental rotation, in healthy women currently using OCs for contraceptive purposes (n = 201) and ...
Elizabeth Hampson   +5 more
doaj   +1 more source

On the effects of testosterone on brain behavioral functions

open access: yesFrontiers in Neuroscience, 2015
Testosterone influences the brain via organizational and activational effects. Numerous relevant studies on rodents and a few on humans focusing on specific behavioral and cognitive parameters have been published.
Peter eCelec   +2 more
doaj   +1 more source

CaMKII is a modulator in neurodegenerative diseases and mediates the effect of androgen on synaptic protein PSD95

open access: yesFrontiers in Genetics, 2022
Androgens rapidly regulate synaptic plasticity in hippocampal neurones, but the underlying mechanisms remain unclear. In this study, we carried out a comprehensive bioinformatics analysis of functional similarities between androgen receptor (AR) and the ...
Shixiong Mi   +24 more
doaj   +1 more source

Pure Leydig cell tumor of the ovary: a rare presentation of a rare entity in a pregnant patient

open access: yesFuture Science OA
Aim: Leydig cell tumors (LCT) are rare neoplasms that represent less than 0.1% of all ovarian tumors. This tumor usually presents with signs and symptoms of excess androgen levels. Diagnosis is made based on a combination of history, laboratory findings,
Anwar Rjoop   +4 more
doaj   +1 more source

Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake

open access: yesFoods, 2015
Milk is a natural fluid and as such contains small amounts of naturally occurring steroids. Human milk is recommended as the optimal source of nutrients for infants and young children, and it has been associated to several short- and long-term benefits ...
Rocío Barreiro   +4 more
doaj   +1 more source

Estrogen Formation and Inactivation Following TBI: What we Know and Where we Could go

open access: yesFrontiers in Endocrinology, 2020
Traumatic brain injury (TBI) is responsible for various neuronal and cognitive deficits as well as psychosocial dysfunction. Characterized by damage inducing neuroinflammation, this response can cause an acute secondary injury that leads to widespread ...
Kelli A. Duncan
doaj   +1 more source

Integrins and Actions of Androgen in Breast Cancer

open access: yesCells, 2023
Androgen has been shown to regulate male physiological activities and cancer proliferation. It is used to antagonize estrogen-induced proliferative effects in breast cancer cells. However, evidence indicates that androgen can stimulate cancer cell growth
Chung-Che Tsai   +10 more
doaj   +1 more source

Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]

open access: yes, 2010
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y.   +7 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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