Results 31 to 40 of about 247,609 (252)

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

, 2019
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT).
S Cockell (21903122), LW Harries (21821876), B Knight (8211801), DJ Elliott (21860654), P McCullagh (21834896), HZ Oo (21903107), O Thompson (18383604), M Daugaard (21903119), G Hysenaj (21826055), KE Livermore (21860633), S Oltean (21860669), J Munkley (21860627), L Ling (9768971), H Zielinska (21903116), I Ehrmann (21903113), E Scott (7784252), C Dalgliesh (21903104), SRG Krishnan (21903101), J McGrath (13297446), TM Maia (21903110), K Cheung (7940885), M Crundwell (16114124), NL Barbosa-Morais (21903125)   +22 more
core   +6 more sources

Inflammation and NF-κB Signaling in Prostate Cancer: Mechanisms and Clinical Implications

Cells, 2018
Prostate cancer is a highly prevalent form of cancer that is usually slow-developing and benign. Due to its high prevalence, it is, however, still the second most common cause of death by cancer in men in the West.
Jens Staal, Rudi Beyaert
doaj   +1 more source

Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2021
PCOS has a wide range of negative impacts on women’s health and is one of the most frequent reproductive systemic endocrine disorders. PCOS has complex characteristics and symptom heterogeneity due to the several pathways that are involved in the ...
Haigang Ding, Haigang Ding, Juan Zhang, Juan Zhang, Feng Zhang, Feng Zhang, Songou Zhang, Xiaozhen Chen, Wenqing Liang, Qiong Xie   +9 more
doaj   +1 more source

The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers [PDF]

, 2004
<p>Introduction: The androgen receptor (AR) gene exon 1 CAG repeat polymorphism encodes a string of 9–32 glutamines. Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to have an earlier ...
Antoniou, A.C., Spurdle, A.B., Cook, M.R., Purdie, David M., Susan Peock, Hopper, John L., Easton, Douglas, Newman, B, kConFaB, Antoniou, AC, Kelemen, Livia, Tobias, E.S., Smith, Paula, Pandeya, N, Giles, GG, Beth Newman, Giles, Graham, Chenevix-Trench, Georgia, Cook, Margaret, Apicella, Carmel, Nirmala Pandeya, Easton, Douglas F., Melissa C Southey, Southey, M.C., Antoniou, Antonis, Purdie, David, Chenevix-Trench, G, Cook, MR, Peock, Susan, Apicella, C., Giles, G.G., Apicella, C, Purdie, D.M., Xiaoqing Chen, Antoniou, Antonis C., David L Duffy, Margaret R Cook, Duffy, David, Newman, Beth, ABCFS, Duffy, D.L., Pandeya, N., Amanda B Spurdle, Dite, Gillian S., Giles, Graham G., Georgia Chenevix-Trench, Smith, Paula L., Newman, B., Gillian S Dite, Hopper, J.L., John L Hopper, Southey, MC, Chen, Xiaoqing, Chen, X., Cook, Margaret R., Chen, X, Duffy, David L., EMBRACE Study Collaborators, Purdie, DM, Hopper, JL, Easton, D.F., Dite, Gillian, Douglas F Easton, David M Purdie, Southey, Melissa, Smith, P.L., AJBCS, Chenevix-Trench, G., Dite, GS, Spurdle, Amanda, Peock, S., Antonis C Antoniou, Chevenix-Trench, Georgia, Dite, G.S., Spurdle, Amanda B., Carmel Apicella, Spurdle, AB, Kelemen, L., Pandeya, Nirmala, Smith, PL, Kelemen, L, Easton, DF, Southey, Melissa C., Paula L Smith, Hopper, John, Livia Kelemen, Duffy, DL, Peock, S, Graham G Giles   +88 more
core   +3 more sources

Androgen dysfunction in non-alcoholic fatty liver disease: Role of sex hormone binding globulin

Frontiers in Endocrinology, 2022
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in the world. It is linked mainly to insulin resistance and metabolic syndrome including obesity and dyslipidemia.
Myeong Jun Song, Jong Young Choi
doaj   +1 more source

The CAG trinucleotide repeat length in the androgen receptor does not predict the early onset of prostate cancer [PDF]

, 2002
Objective To relate the repeat length of the androgen-receptor CAG trinucleotide to the age of onset of prostate cancer, stage and grade of disease. Patients and methods After obtaining ethical approval, 265 patients with locally confined or locally ...
Paterson, P.J., Underwood, M.A., Mir, K., Edwards, J., Bartlett, J.M.S., Hehir, M.   +5 more
core   +1 more source

Clinical, Hormonal and Genetics Features in patients with Androgen Insensitivity Syndrome in Cytogenetic Laboratories in Semarang [PDF]

, 2006
Androgen insensitivity syndrome (AIS) is an X-linked disorder caused by impaired Androgen Receptor (AR) which is encoded in Xq 11-12. In this condition, although the androgen is produced sufficiently, but the peripheral masculinizing effect is blocked ...
Tonang, Alvin
core   +1 more source

Relationship between Maternal Serum Androgen Levels and Success Rate in ICSI Procedure

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Androgens play a key role in growth of ovarian follicles and female fertility in the process of in vitro fertilization.
Sepideh Peyvandi, Marzieh Zamaniyan, Noushin Gordani, Maryam Kharazizadeh, Abolghasem Ajami   +4 more
doaj  

Adrenal gland involvement in 11-ketotestosterone production analyzed using LC-MS/MS

Frontiers in Endocrinology, 2023
Introduction11-ketotestosterone (11KT), which is derived by the bioconversion of testosterone via 11β-hydroxytestosterone (11OHT), is a potent agonist of the human androgen receptor.
Kento Ikegawa, Kento Ikegawa, Yukihiro Hasegawa, Yukihiro Hasegawa   +3 more
doaj   +1 more source

The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium [PDF]

, 2008
Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation.
Cartwright, JE, Yliheikkila, M., Marius C. Jones, Lam, Eric W.-F., Eric W.-F. Lam, Matti Poutanen, Fusi, L, Luca Fusi, Kim, J. J., Ho, K.-K., Teklenburg, G., Kim, JJ, Poutanen, M, Trew, G, Lavery, S., Cartwright, J. E., Judith E. Cartwright, Cloke, B, Kajihara, T, Geoffrey Trew, Takeshi Kajihara, Huhtinen, K., Jones, M. C., Stuart Lavery, Lam, EW, Jan J. Brosens, Huhtinen, K, Lavery, S, J. Julie Kim, Trew, G., Poutanen, M., Kaisa Huhtinen, Kajihara, T., Brosens, Jan J., Cloke, B., Ho, KK, Teklenburg, G, Jones, MC, Brosens, JJ, Yliheikkilä, M, Maria Yliheikkilä, Gijs Teklenburg, Brianna Cloke, Ka-Kei Ho, Fusi, L.   +44 more
core   +1 more source