Results 171 to 180 of about 19,533 (266)

Serendipity, steroids and science. [PDF]

J Steroid Biochem Mol Biol
Sharifi N.
europepmc   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

Clinical implication of immune check point inhibitors in advanced prostate cancer: insight from the KEYNOTE-991 trial. [PDF]

Transl Androl Urol
Yamada Y.
europepmc   +1 more source

The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley   +1 more source

The future of androgen receptor targeting in prostate cancer: third-generation inhibitors and beyond. [PDF]

Ther Adv Med Oncol
Bernard-Tessier A, Naoun N, Barraud S, Flippot R, Pobel C, Rey M, Baldini C, Massard C, Patrikidou A, Fuerea A, Di Palma M, Albigès L, Loriot Y, Fizazi K.   +13 more
europepmc   +1 more source

Judicial demands for prostate cancer treatment in Brazil: androgen receptor pathway inhibitors are an urgent public health problem. [PDF]

Einstein (Sao Paulo)
Silveira MAD, Ricomini CO, Silva RCD, Moreira FT, Pedrotti CHS, Teich VD, Barros LHC, Glina S, Korkes F.   +8 more
europepmc   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models. [PDF]

Int J Mol Sci
Montes de Oca C, Álvarez L, Aceves C, Anguiano B.   +3 more
europepmc   +1 more source

Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease

Diabetes, Obesity and Metabolism, EarlyView.
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl, Kamlesh Khunti, Chantal Mathieu   +2 more
wiley   +1 more source