Results 131 to 140 of about 2,496,118 (309)
Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer
, 2016 James K. Johnson, Erin M. Skoda, Jianhua Zhou, Erica Parrinello, Dan Wang, Katherine J. O’Malley, Benjamin R. Eyer, Mustafa Zahrittin Kazancioğlu, Kurtis Eisermann, Paul A. Johnston, Joel B. Nelson, Zhou Wang, Peter Wipf +12 moreopenalex +1 more sourceData from Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer
, 2023 Ricardo M. Attar, Maria Jure‐Kunkel, Aaron Balog, Mary Ellen Cvijic, Janet Dell-John, Cheryl A. Rizzo, Liang Schweizer, Thomas Spires, J. Suso Platero, Mary T. Obermeier, Weifang Shan, Mark Salvati, William R. Foster, Joseph Dinchuk, Shen-Jue Chen, Gregory D. Vite, Robert Krämer, Marco M. Gottardis +17 moreopenalex +1 more sourceEnzalutamide for the Treatment of Androgen Receptor-Expressing Triple-Negative Breast Cancer.
Journal of Clinical Oncology, 2018 T. Traina, K. Miller, D. Yardley, J. Eakle, L. Schwartzberg, J. O’Shaughnessy, W. Gradishar, P. Schmid, E. Winer, C. Kelly, R. Nanda, A. Gucalp, A. Awada, L. García-Estévez, M. Trudeau, J. Steinberg, H. Uppal, I. C. Tudor, A. Peterson, J. Cortés +19 moresemanticscholar +1 more sourceNatural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy
Food Frontiers, EarlyView.Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus +8 morewiley +1 more sourceSurvival Analysis and Immunohistochemical Study of HER-2 and AR (Androgen Receptor) Expression in Salivary Duct Carcinoma
, 2013 Kuninori Otsuka, Yorihisa Imanishi, Noboru Habu, Yoichiro Sato, Seiji Shigetomi, Ryoichi Fujii, Koji Sakamoto, Toshiki Tomita, Masato Fujii, Kaori Kameyama, Kaoru Ogawa +10 moreopenalex +2 more sourcesNatural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential
Food Frontiers, EarlyView.The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho +15 morewiley +1 more sourcePotential endocrine-disrupting effects of iprodione via estrogen and androgen receptors: evaluation using in vitro assay and an in silico model
Applied Biological ChemistryThis study was conducted to provide evidence, using in vitro and in silico testing methods, regarding the adverse effects of iprodione, a representative dichlorophenyl dicarboxamide fungicide, on the endocrine system.Ji-Yeon Yang, Jeong-Hyun Lim, Soo-Jin Park, Youmi Jo, Si Young Yang, Min-Kyoung Paik, So-Hye Hong +6 moredoaj +1 more source
