Results 141 to 150 of about 113,908 (219)

Saruparib in combination with androgen receptor pathway inhibitors in metastatic hormone-sensitive prostate cancer: EvoPAR-Prostate01. [PDF]

Future Oncol
Azad AA, Agarwal N, Armstrong AJ, Hellmis E, Sugimoto M, Ürün Y, Xing N, Aregay M, Lima J, Meulendijks D, Chi KN.   +10 more
europepmc   +1 more source

Quantification of steroid hormones in free‐ranging Apennine wolf Canis lupus italicus hair samples collected post‐mortem

Wildlife Biology, EarlyView.
After decades of dramatic reductions in their populations, Italian wolves have begun recolonizing parts of their historic range. This growth in populations can lead to potential conflicts with human activities, which remain the main cause of wolf mortality.
Ilaria Troisio, Carmela Musto, Nicola Acquisti Casi, Nadia Govoni, Giuseppe Merialdi, Domenico Ventrella, Alberto Elmi, Mauro Delogu, Maria Laura Bacci   +8 more
wiley   +1 more source

Identification of a Novel Trifluoromethyl-Bearing Flavonoid as a Promising Androgen Receptor Antagonist: Structure-Based Virtual Screening and In Vitro Study. [PDF]

Comput Struct Biotechnol J
Tadasee P, Khotavivattana T, Chaithirayanon K, Assawakosri S, Nutho B.   +4 more
europepmc   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Blood-Brain Barrier (BBB)-Penetrable Androgen Receptor (AR) Degrader as a Potential Therapeutic Agent for Glioblastoma. [PDF]

ACS Pharmacol Transl Sci
Zhao X, Li Y, Martin WR, Salem F, Korem R, Bolbol S, Worden G, Sajid M, Al-Rousan A, Wilt B, Zhang W, Turchyn L, Hubert C, Ning L, Lathia JD, Zhou A, Su B.   +16 more
europepmc   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Assessing the prognostic role of androgen receptor expression in non-metastatic triple-negative breast cancer. [PDF]

Front Oncol
Al-Masri M, Safi Y, Aljalabneh B, Jarah I, Ananzeh H, AlMasri R, Alayyan O, Alawneh F, Almasri M.   +8 more
europepmc   +1 more source

Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression: A Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the effects of Clinical Pilates (CP) training and aerobic exercise (AE) on menopausal symptoms, depressive symptoms, quality of life (QoL), and sleep quality in postmenopausal women. Design Parallel‐group randomised controlled trial. Setting A Healthy Life Center in Bitlis, Turkey.
Başak Can, Serkan Usgu, Günseli Usgu
wiley   +1 more source