Results 231 to 240 of about 210,919 (300)

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the androgen receptor signaling pathway. [PDF]

Cell Mol Life Sci
Liu P, Wang B, Liu H, Liu L, Sun F, Sui P, Hu J, Gao L, Han B.   +8 more
europepmc   +1 more source

Prostatic stromal tumors with uncertain malignant potential: A scoping review of clinical challenges and management strategies

UroPrecision, EarlyView.
Abstract Prostatic stromal tumor of uncertain malignant potential (STUMP) is a rare neoplasm arising from specialized prostatic stromal cells with a broad range of histologic patterns and unpredictable clinical behavior. It is often challenging to distinguish STUMP from prostatic stromal sarcoma due to morphological similarities, necessitating specific
Ibrahim A. Khalil, Abdullah M. Al‐Jubouri, Khaled Murshed, Ahmad R. Al‐Qudimat, Majd Alkabbani, Nagy Younes, Khalid Al Jalham, Khalid Al Rumaihi   +7 more
wiley   +1 more source

Androgen receptor-dependent DRAM1 activation drives autophagic resistance to BRAF inhibitors in BRAFV600-mutant melanoma. [PDF]

Cell Death Dis
Zhi D, Wu B, Yang J, Wang D, Qiao J, Guo F.   +5 more
europepmc   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Metastatic prostate cancer recurrence within a percutaneous computed tomography guided needle biopsy tract: A rare case report

UroPrecision, EarlyView.
Abstract Background Metastatic prostate cancer tumor seeding within a percutaneous biopsy tract is rare. While reports of tumor seeding following perineal and transrectal prostate biopsies exist, no cases of prostate cancer tumor seeding along a metastatic percutaneous bone biopsy tract detected by prostate specific membrane antigen (PSMA) positron ...
Thomas Neerhut, Thomas McMaster, Abigail Attwell‐Heap, Michael Kreltszheim   +3 more
wiley   +1 more source

Significance of androgen receptor and its potential for anti-androgen/androgen receptor-antagonist therapy in ovarian cancers. [PDF]

PLoS One
Kim TH, Memarzadeh S, Vahdatshariatpanahi S, Ostrzega N, Kang Y, Moatamed NA.   +5 more
europepmc   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth. [PDF]

Oncol Lett
Chen X, Gong X, Zhang J, Liu W.
europepmc   +1 more source