Results 221 to 230 of about 140,287 (313)

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi   +6 more
wiley   +1 more source

Tumor proliferation associates with greater sensitivity to androgen receptor pathway inhibition in metastatic prostate cancer. [PDF]

open access: yesJ Clin Invest
Mendes L   +19 more
europepmc   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó   +9 more
wiley   +1 more source

EE2 and the Fish Brain: Age‐Dependent Impact of 17α‐Ethinylestradiol on Brain Cell Proliferation and Behavior in Sea Bass Larvae

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia   +6 more
wiley   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

Identification of CAND1 as a DNA-dependent protein kinase-regulated coactivator of androgen receptor and the ARv7 splice variant. [PDF]

open access: yesPLoS One
Hamilton RA   +10 more
europepmc   +1 more source

Androgen receptor [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

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