Results 161 to 170 of about 17,593 (256)

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua, Xinyi Wu, Tahani Al Kindi, Bulent O. Yildiz, Aya Mousa, Loyal Pattuwage, Helena Teede, Anju E. Joham, Chau Thien Tay   +8 more
wiley   +1 more source

Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity. [PDF]

Curr Issues Mol Biol
Calderón Guzmán D, Osnaya Brizuela N, Juárez Olguín H, Ortiz Herrera M, Valenzuela Peraza A, Hernández Garcia E, Chávez Riveros A, Calderón Morales S, Rojas Ochoa A, Silva Ortiz A, Santes Palacios R, Dorado Gonzalez VM, García Ortega D.   +12 more
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Precision Targeted Therapy for PCOS: Emerging Drugs, Translational Challenges, and Future Opportunities. [PDF]

Biomedicines
Wu X, Yi W, Liu X.
europepmc   +1 more source

Algorithms in Allergy: Hereditary Angioedema

Allergy, EarlyView.
Konrad Bork, Markus Magerl, Emel Aygören‐Pürsün, Henriette Farkas   +3 more
wiley   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer. [PDF]

Research (Wash D C)
Ye J, Xie Y, Wang J, Wu R, Li D, Yoo KH, Wusiman D, Cho WC, Lyu Z, Feng D.   +9 more
europepmc   +1 more source

The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley   +1 more source

Androgen Receptor Signaling Inhibitors for Metastatic Hormone Sensitive Prostate Cancer in Asians: Indirect Comparison. [PDF]

Cancer Rep (Hoboken)
Chen W, Yoshida S, Fujii Y.
europepmc   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source