Results 151 to 160 of about 124,766 (300)

Design, Synthesis and biological evaluation of novel acridine-polyamine conjugates against prostate cancer [PDF]

, 2009
Prostate cancer is the most common cause of cancer death in men, aged 85 and over. Androgen receptor, a single polypeptide with three functional domains is very important during initiation and progression of the disease.
Karodia, N, Maurice, HB, Phillips, Roger
core  

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

[Androgen receptor]. [PDF]

Nihon rinsho. Japanese journal of clinical medicine, 2011
Akira, Komiya, Akihiko, Watanabe, Kenji, Yasuda, Hideki, Fuse   +3 more
openaire   +3 more sources

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Expression Rates of Sex Hormone Receptors with Their Clinical Correlates in Gastric Cancer Patients and Normal Controls

The World Journal of Men's Health
Purpose: Sex hormones affect development and prognosis of gastric cancer (GC). This study aimed to compare the sex hormone receptor expression between control and GC, and to evaluate its correlation with patient characteristics.
Yonghoon Choi, Nayoung Kim, Ji Hyun Park, Chin-Hee Song, Hyeon Jeong Oh   +4 more
doaj   +1 more source

Liver X Receptor α (LXRα) Regulates 5β‐Reductase (AKR1D1) Expression in Avian Embryos: Implications for Yolk Steroid Metabolism

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Steroid‐mediated maternal effects are well‐studied as a source of phenotypic variation. In bird eggs, the yolk contains various steroids that can influence embryonic development. However, one complicating factor in understanding how yolk steroids affect development is that the embryo metabolizes yolk steroids to regulate exposure.
Ryan T. Paitz, Sara E. Waters, Delaney K. Reynolds, Emily M. Drew, Emily P. Harders   +4 more
wiley   +1 more source

Ovulating Female of Nine‐Spined Sticklebacks (Pungitius sinensis) Are Attracted to Substances Derived From Male Kidneys

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Male sticklebacks (Gasterosteidae) produce an adhesive protein called “spiggin” in the tubular epithelial cells of their kidneys, which they use to attach plants or plant debris together and build nesting sites. Spiggin is a glycoprotein excreted in urine.
Miki Nagaya, Hidenobu Yambe, Yasunori Koya   +2 more
wiley   +1 more source

Androgen receptors in the forebrain: A study in adult male cats. [PDF]

J Morphol, 2023
Coolen RL, Cambier JC, van Asselt E, Blok BFM.   +3 more
europepmc   +1 more source