Results 151 to 160 of about 73,737 (266)

Conformational dynamics of androgen receptors bound to agonists and antagonists. [PDF]

Sci Rep, 2021
Gim HJ, Park J, Jung ME, Houk KN.
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Androgen receptors protect against thoracic aortic dissection via inhibiting ferroptosis of vascular smooth muscle cells in male patients. [PDF]

Chin Med J (Engl)
Ni Q, Wang Y, Qi H, Yao Y, Lu Z, Wang W, Yang S, Chen J, Li Y, Lyv L, Zhao Y, Ye M, Xue G, Tang WH, Ye Y, Guo X, Zhang L.   +16 more
europepmc   +1 more source

Anti-Alopecia Activity of Coumarin Derivatives Isolated from Merremia peltata Leaves and Computational Study of Their Binding to Androgen Receptors Using Molecular Docking and Molecular Dynamic Simulation. [PDF]

Pharmaceuticals (Basel), 2023
Abdurrahman S, Ruslin R, Hasanah AN, Ifaya M, Mustarichie R.   +4 more
europepmc   +1 more source

Sex-Dependent Regulation of Liver Fibrosis in Primary Sclerosing Cholangitis: The Role of miR-125b, Androgen Receptors, TGF-β, and Apelin Signalling. [PDF]

Int J Mol Sci
Abramczyk J, Milkiewicz M, Łaba A, Milkiewicz P, Banales JM, Kempinska-Podhorodecka A.   +5 more
europepmc   +1 more source

Selenium Nanoparticles Modulate Steroidogenesis-Related Genes and Improve Ovarian Functions via Regulating Androgen Receptors Expression in Polycystic Ovary Syndrome Rat Model. [PDF]

Biol Trace Elem Res, 2023
Abdallah ABE, El-Ghannam MA, Hasan AA, Mohammad LG, Mesalam NM, Alsayed RM.   +5 more
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Characterization of lncRNA-protein interactions associated with Prostate cancer and Androgen receptors by molecular docking simulations. [PDF]

Biochem Biophys Rep
Khilwani B, Kour B, Shukla N, Vuree S, Ansari AS, Lohiya NK, Suravajhala P, Suravajhala R.   +7 more
europepmc   +1 more source

Resistance training protects against muscle pain through activation of androgen receptors in male and female mice. [PDF]

Pain, 2022
Lesnak JB, Fahrion A, Helton A, Rasmussen L, Andrew M, Cunard S, Huey M, Kreber A, Landon J, Siwiec T, Todd K, Frey-Law LA, Sluka KA.   +12 more
europepmc   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source