Results 121 to 130 of about 238,876 (343)

The Influence of β-Carotene and Its Liposomal Form on the Expression of EMT Markers and Androgen-Dependent Pathways in Different Prostate Cell Lines

open access: yesAntioxidants
Prostate cancer (PCa) is the most common malignancy in men. Although the prognosis in the early stages is good, the treatment of advanced PCa remains a formidable challenge.
Joanna Dulińska-Litewka   +7 more
doaj   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

THE EFFECT OF AGE, SEX, AND ANDROGEN ON BLOOD ERGOTHIONEINE

open access: hybrid, 1957
Julia B. Mackenzie, Cosmo G. Mackenzie
openalex   +1 more source

Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary.

open access: yesHuman Reproduction Update, 2016
D. Dewailly   +5 more
semanticscholar   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

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