Results 121 to 130 of about 238,876 (343)
Androgens: Biochemistry, Physiology and Clinical Significance. Ralph I. Dorfman and Reginald A. Shipley. New York, John Wiley & Sons, Inc. pp. 590, $13.50. 1958 [PDF]
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Prostate cancer (PCa) is the most common malignancy in men. Although the prognosis in the early stages is good, the treatment of advanced PCa remains a formidable challenge.
Joanna Dulińska-Litewka+7 more
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Sex differences in androgen sulphate formation in rats and mice [PDF]
David A. Lewis
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Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano+6 more
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THE EFFECT OF AGE, SEX, AND ANDROGEN ON BLOOD ERGOTHIONEINE
Julia B. Mackenzie, Cosmo G. Mackenzie
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The effect of nutrition and androgens on the composition of bovine blood plasma and seminal plasma at puberty [PDF]
Stamatis Baronos+3 more
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Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
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EFFECT OF ANDROGENS ON PLASMA LEVELS OF 17-HYDROXYCORTICOSTEROIDS*
Carl Gemzell, G Notter
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Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert+3 more
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