Hormones and Signaling Pathways Involved in the Stimulation of Leydig Cell Steroidogenesis
Endocrines, 2023 Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health.
Karine de Mattos +2 more
doaj +1 more source
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
, 2016 This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
A Potential Role and Contribution of Androgens in Placental Development and Pregnancy
Life, 2021 Successful pregnancy requires the establishment of a highly regulated maternal–fetal environment. This is achieved through the harmonious regulation of steroid hormones, which modulate both maternal and fetal physiology, and are critical for pregnancy ...
Agata M. Parsons, Gerrit J. Bouma
doaj +1 more source
Muscle Growth and Anabolism in Intensive Care Survivors (GAINS) trial: a pilot randomised controlled trial [PDF]
Acute and Critical Care, 2022 Background To explore the feasibility, safety, and potential benefits of administration of the anabolic steroid nandrolone to patients in the recovery phase from critical illness weakness.
Matthew H Anstey +9 more
doaj +1 more source
Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]
, 2017 BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de +5 more
core +1 more source
Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]
, 2012 Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner +11 more
core +1 more source
WAO guideline for the management of hereditary angioedema [PDF]
, 2012 Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel +17 more
core +1 more source
The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]
, 2020 Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K +3 more
core
Evidence of the indirect hormonal activity of prohormones using liver S9 metabolic bioactivation and an androgen bioassay [PDF]
, 2008 Prohormones such as dehydroepiandrosterone (DHEA) are steroid precursors that do not show hormonal activity by themselves. Abuse of these prohormones in cattle fattening is hard to prove because of strong in vivo metabolism and the difficulty to detect ...
Bovee, T.F.H. +4 more
core +2 more sources
Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis [PDF]
, 2015 PURPOSE: Vernal keratoconjunctivitis (VKC) is a chronic allergic disease mainly affecting boys in prepubertal age and usually recovering after puberty.
Bonini, S. +4 more
core +4 more sources