Results 31 to 40 of about 238,876 (343)
Androgen Signaling in Uterine Diseases: New Insights and New Targets
Biomolecules, 2022 Common uterine diseases include endometriosis, uterine fibroids, endometrial polyps, endometrial hyperplasia, endometrial cancer, and endometrial dysfunction causing infertility.
Mu Lv +8 more
doaj +1 more source
Journal of Clinical Medicine, 2018 The role of testosterone in the pathophysiology of inflammation is of critical clinical importance; however, no universal mechanism(s) has been advanced to explain the complex and interwoven pathways of androgens in the attenuation of the inflammatory ...
A. Traish +4 more
semanticscholar +1 more source
Androgens and ovarian function: translation from basic discovery research to clinical impact.
Journal of Endocrinology, 2019 In the last decade it has been revealed that androgens play a direct and important role in regulating female reproductive function. Androgens mediate their actions via the androgen receptor (AR), and global and cell-specific Ar knockout mouse models have
K. Walters +3 more
semanticscholar +1 more source
Insights into Androgen Receptor Action in Lung Cancer
Endocrines, 2023 Sex hormones and their receptors play a crucial role in human sexual dimorphism and have been traditionally associated with hormone-dependent cancers like breast, prostate, and endometrial cancer.
Darko Durovski +2 more
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11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome
Journal of Clinical Endocrinology and Metabolism, 2016 Context: Androgen excess is a defining feature of polycystic ovary syndrome (PCOS), but the exact origin of hyperandrogenemia remains a matter of debate.
M. O’Reilly +6 more
semanticscholar +1 more source
A Potential Role and Contribution of Androgens in Placental Development and Pregnancy
Life, 2021 Successful pregnancy requires the establishment of a highly regulated maternal–fetal environment. This is achieved through the harmonious regulation of steroid hormones, which modulate both maternal and fetal physiology, and are critical for pregnancy ...
Agata M. Parsons, Gerrit J. Bouma
doaj +1 more source
POSTMENOPAUSAL HIRSUTISM: A CASE REPORT
Khyber Medical University Journal, 2021 INTRODUCTION: Hirsutism is a common condition affecting around 5-10% of female in the childbearing age. During menopausal evolution phase some terminal hair growth can occur in few females as part of normal aging process.
Tahir Ghaffar +5 more
doaj +1 more source
MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease
European Journal of Endocrinology, 2017 Female androgen excess and male androgen deficiency manifest with an overlapping adverse metabolic phenotype, including abdominal obesity, insulin resistance, type 2 diabetes mellitus, non-alcoholic fatty liver disease and an increased risk of ...
L. Schiffer +3 more
semanticscholar +1 more source
Androgen Receptor and Mechanism of Androgen Action
Annals of Medicine, 1993 Androgen receptor is the intracellular protein that mediates biological actions of physiological androgens (testosterone and 5 alpha-dihydrotestosterone). Androgen receptor belongs to a large family of ligand-dependent proteins whose function is to modulate expression of genes and gene networks in a cell- and tissue-specific manner.
Pekka Kallio +3 more
openaire +3 more sources
Reproductive Biology and Endocrinology, 2011 Background Effects of androgens on follicle maturation have been controversial for some time. Here, we review the potential of their applications in improving human ovulation induction, based on human and animal data, reported in the literature.
Gleicher Norbert +2 more
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