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Androgenetic alopecia (AGA) is the most diagnosed hair loss dysfunction. Its physiopathology comprises a genetic predisposition affording an exacerbated response of the hair follicles cells to androgens aggravated by scalp inflammation and extrinsic ...
Tatiele Katzer+3 more
semanticscholar +1 more source
Gastropod mollusks have been proposed as alternative models for male reproductive toxicity testing, due to similarities in their reproductive anatomy compared to mammals, together with evidence that endocrine disrupting chemicals can cause effects in ...
Satwant Kaur+6 more
doaj +1 more source
Androgen receptors beyond prostate cancer: an old marker as a new target. [PDF]
Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary effects in this malignancy.
Kurzrock, Razelle+2 more
core +2 more sources
Androgens have an intense consequence on the human scalp and body hair. Scalp hair sprouts fundamentally in awol of androgens whereas the body hair hike is vulnerable to the activity of androgens.
Sumel Ashique+3 more
doaj +1 more source
Androgens during the reproductive years, what's normal for women?
IMPORTANCE Whether serum androgens identify women with 'androgen insufficiency' or 'androgen excess' is unresolved, as what constitutes normal remains uncertain.
M. Skiba+5 more
semanticscholar +1 more source
Androgen Signaling in Uterine Diseases: New Insights and New Targets
Common uterine diseases include endometriosis, uterine fibroids, endometrial polyps, endometrial hyperplasia, endometrial cancer, and endometrial dysfunction causing infertility.
Mu Lv+8 more
doaj +1 more source
The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways [PDF]
Prostate cancer is the second leading cause of cancer related deaths in men from the western world. Treatment of prostate cancer has relied on androgen deprivation therapy for the past 50 years.
Bakin RE+9 more
core +4 more sources
High concentrations of glucocorticoids caused by chronic stress are known to affect ovarian function and cause diminished ovarian reserve. Androgens are essential for early-stage ovarian follicle development, but the effects and mechanisms of androgens ...
Lingyun Gao+5 more
doaj +1 more source
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma [PDF]
Asthma resistance to glucocorticoid treatment is a major health problem with unclear etiology. Glucocorticoids inhibit adrenal androgen production. However, androgens have potential benefits in asthma. HSD3B1 encodes for 3β-hydroxysteroid dehydrogenase-1
Alyamani, Mohammad+31 more
core +2 more sources
Androgenetic alopecia: a review [PDF]
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma+7 more
core +1 more source