Results 31 to 40 of about 3,980 (182)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Diterpenoids and Flavonoids from Andrographis paniculata.

Chemical & pharmaceutical bulletin, 2020
Chemical investigation of the aerial parts of Andrographis paniculata resulted in isolation of nine compounds, including a new ent-labdane diterpenoid, andrographic acid methyl ester (1), a new chalcone glucoside, pashanone glucoside (5), and seven known metabolites, andrograpanin (2), andrographolide (3), andropanolide (4), andrographidine A (6 ...
Hanh, Tran Thi Hong, My, Nguyen Thi Thuy, Cham, Pham Thi, Quang, Tran Hong, Cuong, Nguyen Xuan, Huong, Tran Thu, Nam, Nguyen Hoai, Minh, Chau Van   +7 more
openaire   +2 more sources

Vibrational Dynamics of the Diterpene-Neoandrographolide

E-Journal of Chemistry, 2009
A complete normal coordinate analysis was performed for neoandrographolide in terms of the calculation by using Wilson’s G-F matrix method and Urey Bradley force field.
P. K. Singh, Tanveer Hasan, Neeraj Misra
doaj   +1 more source

The Protective Effect of Andrographis paniculata Against Lipopolysaccharide-induced Sepsis in Lung Tissues of a Rat Model Through the Decrease of ICAM-1 and E-selectin Expression

Indonesian Biomedical Journal, 2023
BACKGROUND: Andrographis paniculata has anti-inflammatory, anti-cancer, and immunomodulatory effects. Intercellular adhesion molecule-1 (ICAM-1) and E-selectin are released in inflammatory conditions due to sepsis.
Michael Kevin, Nyoman Suci Widyastiti, Selamat Budijitno, Yan Wisnu Prajoko, Neni Susilaningsih   +4 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Pengujian validasi analisis kadar andrografolid secara kromatografi cair kinerja tinggi (KCKT) dengan eluasi gradien terhadap ekstrak herba sambiloto (Andrographis panuculata Ness)

Journal of Biological Researches, 2012
Andrographolide of Andrographis paniculata Nees have been isolated and determined Extraction was carried out by maceration with ethanol as solvent.
Toetik Aryani
doaj   +1 more source

Antagonistic effects of Andrographis paniculata methalonic extract on chromium-induced membrane damage in male Albino rats [PDF]

Journal of Stress Physiology & Biochemistry, 2022
The occurrence of heavy metals in the environment and their enormous industrial use has led to an increase in the frequency of the human organ toxicity.
S. K. Dey
doaj  

A review on selected herbal plants as alternative anti-diabetes drugs: chemical compositions, mechanisms of action, and clinical study

International Journal of Food Properties, 2023
Herbal utilization, as an antidiabetes agent, is an interesting topic to find acceptable herbal drugs to decrease blood glucose levels. The aim of this review is to evaluate the potency of selected herbal medicines to reduce blood glucose levels and to ...
Mustofa Ahda, Irwandi Jaswir, Alfi Khatib, Qamar Uddin Ahmed, Nurkhasanah Mahfudh, Yunita Dewi Ardini   +5 more
doaj   +1 more source

A critical review of Andrographis paniculata

Medicinal Plant Biology, 2023
Andrographis paniculata, a traditional medicinal plant, is widely used to treat various disorders. According to traditional Chinese medicine (TCM) theory, it is intensely bitter in taste and cold-natured. Andrographolide and its derivates are the major bioactive compounds that show anti-inflammatory, anti-tumor, anti-diabetes, cardiovascular protection,
Xianghui Chen, Junze Ren, Jindong Yang, Zhanpin Zhu, Ruibing Chen, Lei Zhang   +5 more
openaire   +1 more source

TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley   +1 more source