Results 31 to 40 of about 1,570 (204)

Assessment of Annona muricata Phytochemicals as 17β‐HSD1 Inhibitors through Molecular Docking, Dynamics Simulation, DFT, and ADMET Analyses

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Breast cancer remains a leading cause of female mortality, largely sustained by local oestrogen production. The enzyme 17β‐hydroxysteroid dehydrogenase type 1 (17β‐HSD1) is an enzyme involved in the oestrogen biosynthesis pathway, particularly in the conversion of estrone to estradiol, and is overexpressed in conditions such as breast cancer ...
Emad Rashad Sindi, Md Jannatul Islam Polash, Guilherme Bastos Alves, Imren Bayil, Samson Olusegun Afolabi, Hanan M. Alharbi, Alaa A. Khojah, Jonas Ivan Nobre Oliveira, Aamal A. Al‐Mutairi, Magdi E. A. Zaki   +9 more
wiley   +1 more source

A vizuális arcfelismerés és az olfaktoros információ feldolgozásának cross-modális szenzoros interakciója = Cross-model sensory integration of visual face processing and olfactory information [PDF]

, 2010
Pályázatunk célja az volt, hogy adatokat szolgáltasson az emberi arcok kódolásáról és feltárja a vizuális és az olfaktoros percepció integrációját. Az arcfeldolgozás kérgi mechanizmusait magas-szintű utóhatások által kiváltott adaptációs folyamatok ...
Kovács, Gyula, Pléh, Csaba, Vidnyánszky, Zoltán   +2 more
core  

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen, Volume 14, Issue 9, September 2025.
Two genetically modified strains are designed and constructed to produce 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) by disrupting and overexpressing the aldolase gene (thl) in the genetically modified strains of Mycolicibacterium neoaurum NRRL B‐3805, respectively, which are useful ...
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
wiley   +1 more source

Family Scents: Developmental Changes in the Perception of Kin Body Odor? [PDF]

, 2018
There is increasing evidence that human body odors are involved in adaptive behaviors, such as parental attachment in infants or partner choice in adults.
Ferdenzi, Camille, Roberts, S., Schaal, Benoist   +2 more
core  

Effect of Androstene Derivatives on Metacorticoid Hypertension

Experimental Biology and Medicine, 1953
SummarySix derivatives of 4-androsten-3-one were tested for depressor activity in metacorticoid hypertensive rats. Replacement of the 11-hydroxyl by hydrogen or a keto group appeared to decrease the activity of the 17-ketosteroids and increase the activity of the 17-hydroxysteroids.
openaire   +2 more sources

Improving the Determination of Carbon Isotope Ratios of Endogenous Steroids Found in Human Serum

Drug Testing and Analysis, Volume 17, Issue 7, Page 944-953, July 2025.
A method employing high‐performance liquid chromatographic sample cleanup to determine the carbon isotope ratios of steroids found in human serum was developed and fully validated. A reference population encompassing more than 120 male and female athlete samples was investigated in order to establish population‐based thresholds for Δ‐values.
Thomas Piper, Mario Thevis
wiley   +1 more source

Towards an assay for allelic inactivation of vomeronasal receptor genes in mouse [PDF]

, 1998
Thesis (S.M.)--Massachusetts Institute of Technology, Dept.
Lee, Tien-Yi, 1970-
core  

Multiyear Baleen Endocrine Profiles Suggest a Longer Estimated Gestation in Southern Right Whales (Eubalaena australis)

Ecology and Evolution, Volume 15, Issue 6, June 2025.
Multiyear profiles of progesterone and estrogen in the baleen of adult female southern right whales indicate progesterone elevations lasting on average between 20 and 25 months, indicative of pregnancies longer than previously estimated. These data are in line with endocrine profiles in baleen of other Balaenid whales incl.
Loraine Shuttleworth, Andre Ganswindt, Kathleen E. Hunt, Alejandro Fernández Ajó, Estefan Pieterse, S. Mduduzi Seakamela, Chantel Schoeman, Els Vermeulen   +7 more
wiley   +1 more source

Testosterone Biosynthesis from 4-Androstene-3,17-Dione Catalyzed via Bifunctional Ketoreductase [PDF]

, 2023
Wei Yi, Guangyao Mei, Jinlin Zhao, Shaoyang Zhang, Wenping Qin, Qing Sheng, Zhongyi Yang   +6 more
openalex   +1 more source

C‐type natriuretic peptide promotes human granulosa cell growth and estradiol production: Implications for early follicle development

Reproductive Medicine and Biology, Volume 24, Issue 1, January/December 2025.
This study demonstrated that CNP stimulates human granulosa cell proliferation and the potential for cross‐talk between these cells and oocytes. Further research on the simultaneous administration of CNP and E2 may offer a potential avenue for promoting early‐stage follicle development in infertility treatments for patients with poor ovarian reserve ...
Yorino Sato, Kazuhiro Kawamura
wiley   +1 more source