Results 91 to 100 of about 205,200 (274)
Pulmonary hypertension in adolescents with sickle cell disease [PDF]
, 2016 Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core +1 more source
Haematologica, 2016 Sickle cell anemia is a manifestation of a single point mutation in hemoglobin, but inflammation and pain are the insignia of this disease which can start in infancy and continue throughout life.
Lucile Vincent +5 more
semanticscholar +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear +6 more
wiley +1 more source
Biomedical Research, A Tool to Address the Health Issues that Affect African Populations. [PDF]
, 2013 Traditionally, biomedical research endeavors in low to middle resources countries have focused on communicable diseases. However, data collected over the past 20 years by the World Health Organization (WHO) show a significant increase in the number of ...
Peprah, Emmanuel, Wonkam, Ambroise
core +3 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear +7 more
wiley +1 more source
Preliminares del estudio de la meniscocitemia en Colombia, s. a.
Revista de la Facultad de Medicina, 1943 Otros nombres de la enfermedad: Anemia Falciforme; Drepanocitemia; "Sickle Cell Anemia" y "Sickle Cell 'I'rait" en Estados Unidos. La MENISCOCITEMIA es una enfermedad sanguínea caracterizada por la aparición de eritrocitos en forma de hoz, granos de ...
Benjamín Mera
doaj
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia
PLoS ONE, 2016 Pain is a hallmark feature of sickle cell anemia (SCA) but management of chronic as well as acute pain remains a major challenge. Mouse models of SCA are essential to examine the mechanisms of pain and develop novel therapeutics.
Jianxun Lei +4 more
semanticscholar +1 more source
Does Sickle Cell Anaemia Have a Relationship With Avascular Pulp Necrosis? A Systematic Review
Australian Endodontic Journal, EarlyView.ABSTRACT This systematic review examined the relationship between sickle cell disease (SCD), an inherited genetic hemoglobinopathy, and avascular pulp necrosis (APN) in intact teeth. A comprehensive search of eight electronic databases was performed up to December 2024.
Elidiane Elias Ribeiro +5 more
wiley +1 more source