Results 101 to 110 of about 205,200 (274)

PERIPHERAL BLOOD PICTURE OF SICKLE CELL ANEMIA

open access: yesGomal Journal of Medical Sciences, 2018
Laboratory diagnosis of sickle cell anemia involves phenotypic testing for the presence of the sickle haemoglobin and genetic analysis. Phenotypic tests include sickling test and sickle solubility test. Sickle cell anemia can be diagnosed by the presence
Zahid Ullah
doaj  

J Rare Dis Res Treat [PDF]

open access: yes
Sickle cell disease affects more than 100,000 individuals in the United States, among whom disease severity varies considerably. One factor that influences disease severity is the sickle cell disease genotype.

core  

Genetics education in public health : a case study on sickle cell anaemia in Brazil [PDF]

open access: yes, 2005
A anemia falciforme é a doença genética de maior prevalência na população brasileira e comumente apontada como uma questão de saúde pública. O Brasil tem investido na elaboração de ações no campo da anemia falciforme, dentre as quais se encontram ações ...
Diniz, Debora   +2 more
core   +1 more source

Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People

open access: yesBioethics, EarlyView.
ABSTRACT Genome editing in human embryos could raise new ethical issues by changing future people's narrative and numerical identity. Most philosophers agree that some genetic modifications would have larger effects on identity than others, but they disagree on what criteria might explain these differences and have not supported their claims ...
Derek So, Yann Joly, Robert Sladek
wiley   +1 more source

Sickle cell disease complicating pregnancy: A retrospective study

open access: yesJournal of Dr. NTR University of Health Sciences, 2017
Introduction: Sickle cell disease is an uncommon cause of anemia and jaundice during pregnancy. Sickle cell crisis may lead to several maternal and fetal complications. Aims: To study maternal and fetal complications in pregnant patients with sickle cell
B Kavitha, Basanta H Hota
doaj   +1 more source

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. [PDF]

open access: yes, 2019
ObjectiveMicroglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing ...
Bushong, Trevor   +8 more
core   +2 more sources

Changes in sleep patterns in adolescents are more associated with pubertal indicators than age: A perfect storm with a dash of hormones

open access: yesBritish Journal of Developmental Psychology, EarlyView.
Abstract As they become older, adolescents tend to prefer sleeping and rising later. Yet, it is still unclear if these sleep changes occur due to advancing age or because adolescents are more pubertally mature. This was investigated cross‐sectionally in a sample of 121 Brazilian 9‐to‐17‐year‐olds.
Yessica Alejandra Martínez‐Sánchez   +3 more
wiley   +1 more source

Comprehensive neuropsychological evaluation of children and adolescents with sickle cell anemia: a hospital-based sample

open access: yesRevista Brasileira de Hematologia e Hemoterapia
Background: Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children and adolescents with sickle cell ...
Samantha Nunes   +4 more
doaj   +1 more source

Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease

open access: yesBritish Journal of Haematology, EarlyView.
This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly   +5 more
wiley   +1 more source

Duodenal perforation: an unusual complication of sickle cell anemia

open access: yesThe Pan African Medical Journal, 2014
Duodenal perforation in childhood is a rare condition with a high mortality rate if not treated surgically. Primary gastroduodenal perforation is frequently associated with peptic ulcer and exhibits a positive family history.
Can Acıpayam   +5 more
doaj   +1 more source

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