Results 51 to 60 of about 34,389 (155)

Sickle cell anemia: An update on diagnosis, management and prevention strategies

Indian Journal of Community and Family Medicine, 2018
Sickle cell anemia is the most common disease entity of all the monogenic disorders. This is an autosomal recessive disorder. HbS polymerization, vaso-occlusion, and hemolytic anemia are central to the pathophysiology of sickle cell disease, they ...
Shruti Mishra, Gaurav Chhabra
doaj   +1 more source

Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anemia: a case report

Journal of Medical Case Reports, 2018
Background Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure.
Ehab Hanafy, Duaa Alshareef, Suhaila Osman, Abdullah Al Jabri, Faisal Nazim, Gihan Mahmoud   +5 more
doaj   +1 more source

Sexuality and sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: Sickle cell disease, the most common hereditary blood disease in the world, is the result of an atypical hemoglobin called S (Hb S) which, when homozygous (Hb SS) is the cause of sickle cell anemia.
Viviane de Almeida Côbo, Cibele Alves Chapadeiro, João Batista Ribeiro, Helio Moraes-Souza, Paulo Roberto Juliano Martins   +4 more
doaj  

A Phase Ib open label, randomized, safety study of SANGUINATE™ in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia
Background: Treatment of sickle cell anemia is a challenging task and despite the well understood genetic and biochemical pathway of sickle hemoglobin, current therapy continues to be limited to the symptomatic treatment of pain, supplemental oxygen ...
Hemant Misra, James Bainbridge, John Berryman, Abraham Abuchowski, Kenneth Mauricio Galvez, Luis Fernando Uribe, Angel Luis Hernandez, Nestor Rodolfo Sosa   +7 more
doaj   +1 more source

Association between hemolysis and albuminuria in adults with sickle cell anemia

Haematologica, 2012
Studies have questioned whether renal dysfunction in sickle cell disease is linked to hemolysis-associated vasculopathy. We have investigated renal function and markers of hemolysis in a cohort of 424 adult African-British patients with sickle cell ...
Thomas G. Day, Emma R. Drasar, Tony Fulford, Claire C. Sharpe, Swee Lay Thein   +4 more
doaj   +1 more source

Tracking Telehealth Needs for Individuals With Sickle Cell Disease Through the COVID‐19 Pandemic: A Cross‐Sectional Survey Study

Health Science Reports
Background and Aim Pervasive disparities characterize sickle cell disease (SCD) care, including limited access to SCD specialists. Rapid deployment of remote healthcare provision and support during the COVID‐19 pandemic provides an opportunity to ...
Marsha Treadwell, Lisa Du, Yemi Lawrence, Maxine Gaspar, Kathryn Hassell, Sanjay Shah, Moses Akpan, Nicole Crook, Marcia Taylor, Srila Gopal, For the Pacific Sickle Cell Regional Collaborative   +10 more
doaj   +1 more source

Craniofacial bone abnormalities and malocclusion in individuals with sickle cell anemia: a critical review of the literature

Revista Brasileira de Hematologia e Hemoterapia, 2012
This study aims to critically review the literature in respect to craniofacial bone abnormalities and malocclusion in sickle cell anemia individuals.
Cyrene Piazera Silva Costa, Halinna Larissa Cruz Correia de Carvalho, Erika Bárbara Abreu Fonseca Thomaz, Soraia de Fátima Carvalho Sousa   +3 more
doaj   +1 more source

Silent Infarcts with Sickle Cell Anemia

Pediatric Neurology Briefs, 2002
The effect of transfusion therapy on the risk for new silent infarct or stroke in children with sickle cell anemia and abnormal transcranial Doppler (TCD) ultrasonography was determined at the University of Miami, FL, and other centers in the STOP trial (
J Gordon Millichap
doaj   +1 more source

Adrenal Myelolipoma, Cholelithiasis and Calcified Spleen: Retrospective Diagnosis of Sickle Cell Anemia Using a Novel Triad of Abdominal Imaging Findings

Acta Medica Indonesiana, 2016
Sickle cell anemia is an inherited abnormality of the globin chain with very high prevalence in the Indian subcontinent. A significant proportion of these patients present late in life and are at a risk of complications like acute chest syndrome and ...
Sandeep G Jakhere, Raju S Kumbhar, Harshal V Dhongade   +2 more
doaj   +2 more sources

Comparison of Asymptomatic Brain Lesions Between Thalassemia Major and Sickle Cell Anemia Patients

Medicina
Background and Objectives: This study aimed to identify asymptomatic brain lesions in patients with β-thalassemia major (TM) and sickle cell anemia (SCA) and evaluate the correlation of these lesions with factors such as splenectomy, thrombocytosis, and ...
Derya Yavuz Demiray, Özge Eriş Davut, Gönül Oktay   +2 more
doaj   +1 more source