Results 1 to 10 of about 77,477 (311)

How general anesthetics work: from the perspective of reorganized connections within the brain [PDF]

open access: yesKorean Journal of Anesthesiology, 2022
General anesthesia is critical for various procedures and surgeries. Despite the widespread use of anesthetics, their precise mechanisms remain poorly understood.
Teo Jeon Shin   +2 more
doaj   +1 more source

Cardiac output and the pharmacology of general anesthetics: a narrative review

open access: yesColombian Journal of Anesthesiology, 2023
The relationship between cardiac output and anesthetic drugs is important to anesthesiologists, since cardiac output determines the speed with which a drug infused into the bloodstream reaches its target and the intensity of the drug’s effect.
Elena Simón-Polo   +3 more
doaj   +1 more source

The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]

open access: yesKorean Journal of Anesthesiology, 2022
Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong   +5 more
doaj   +1 more source

General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels. [PDF]

open access: yesPLoS ONE, 2018
General anesthetics are indispensable for effective clinical care. Although, the mechanism of action of general anesthetics remains controversial, lipid bilayers and proteins have been discussed as their targets.
Jun-Ichi Kishikawa   +7 more
doaj   +1 more source

General Anesthetics in Cancer Surgery: Can Anesthesiologists Help the Patient with More than a Safe Sleep

open access: yesMedicina, 2022
Most patients suffering from neoplastic diseases will at some point during their illness be approached surgically. Surgery itself may be unfortunately responsible for tumor proliferation and metastatic spread.
John Michael Bonvini
doaj   +1 more source

Molecular mechanisms of general anesthesia [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj   +1 more source

General Anesthetics Commonly Used for Laboratory Animals

open access: yesShiyan dongwu yu bijiao yixue, 2022
General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao   +5 more
doaj   +1 more source

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

open access: yesNature Communications, 2023
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami   +3 more
doaj   +1 more source

The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]

open access: yesKorean Journal of Anesthesiology, 2014
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee   +6 more
doaj   +1 more source

Volatile anesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration

open access: yesBMC Anesthesiology, 2021
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao   +3 more
doaj   +1 more source

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