Results 1 to 10 of about 77,477 (311)
How general anesthetics work: from the perspective of reorganized connections within the brain [PDF]
General anesthesia is critical for various procedures and surgeries. Despite the widespread use of anesthetics, their precise mechanisms remain poorly understood.
Teo Jeon Shin +2 more
doaj +1 more source
Cardiac output and the pharmacology of general anesthetics: a narrative review
The relationship between cardiac output and anesthetic drugs is important to anesthesiologists, since cardiac output determines the speed with which a drug infused into the bloodstream reaches its target and the intensity of the drug’s effect.
Elena Simón-Polo +3 more
doaj +1 more source
The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
doaj +1 more source
General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels. [PDF]
General anesthetics are indispensable for effective clinical care. Although, the mechanism of action of general anesthetics remains controversial, lipid bilayers and proteins have been discussed as their targets.
Jun-Ichi Kishikawa +7 more
doaj +1 more source
Most patients suffering from neoplastic diseases will at some point during their illness be approached surgically. Surgery itself may be unfortunately responsible for tumor proliferation and metastatic spread.
John Michael Bonvini
doaj +1 more source
Molecular mechanisms of general anesthesia [PDF]
General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj +1 more source
General Anesthetics Commonly Used for Laboratory Animals
General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
doaj +1 more source
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami +3 more
doaj +1 more source
The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee +6 more
doaj +1 more source
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao +3 more
doaj +1 more source

