Results 41 to 50 of about 40,984 (314)

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

Systemic immune effects of anesthetics and their intracellular targets in tumors

Frontiers in Medicine, 2022
According to the result released by the World Health Organization (WHO), non-communicable diseases have occupied four of the top 10 current causes for death in the world.
Ting Luan, Yi Li, Lihui Sun, Lihui Sun, Siqi Xu, Siqi Xu, Haifeng Wang, Jiansong Wang, Chong Li, Chong Li   +9 more
doaj   +1 more source

A method of producing cardiac arrest in the dog. [PDF]

, 1953
Thesis (M.A.)--Boston ...
Ryan, Martin Lester
core   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Ultrasound-Guided Occipital Nerve Blocks as Part of Multi-Modal Perioperative Analgesia in Pediatric Posterior Craniotomies: A Case Series

Children, 2023
Various regional anesthetics have been used for postoperative analgesia for pediatric craniotomy. In this case series, we report retrospectively collected data on postoperative pain and analgesic use in 44 patients who received ultrasound-guided ...
Jordan I. Gaelen, Michael R. King, John Hajduk, Angelica Vargas, David J. Krodel, Ravi D. Shah, Hubert A. Benzon   +6 more
doaj   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Combined use of intravenous anesthetics and hypothermia in treating refractory status epilepticus

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
The primary choice of treating refractory status epilepticus (RSE) is intravenous anesthetics, but the seizures of some patients can not get a good control. Thus, other therapies must be combined.
Guo-ping REN, Ying-ying SU
doaj  

Effect of intravenous versus inhaled anesthetics on blood-brain barrier dysfunction and neuroinflammation in elderly patients undergoing major surgery: study protocol of a randomized controlled trial

Trials
Background Postoperative cognitive dysfunction (POCD) is one of the major complications after surgery, with devastating clinical outcomes. Although POCD is a condition with a multifactorial pathophysiology, blood-brain barrier (BBB) dysfunction and ...
Wongook Wi, Hyo-Jin Kim, Sira Bang, Oh Joo Kweon, Doyeon Kim, Eun Jung Oh   +5 more
doaj   +1 more source

Risk factors for postoperative nausea and vomiting after the removal of impacted third molars: a cross-sectional study

BMC Oral Health, 2021
Background A better understanding of the risk factors for postoperative nausea and vomiting (PONV) could improve patient outcomes. This study aimed to analyze the risk factors for PONV and its onset after third molar impaction surgery, and to demonstrate
Hiroaki Hasegawa, Atsushi Abe, Hiroki Hayashi, Hiroshi Furuta, Takanori Ishihama   +4 more
doaj   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source