Results 41 to 50 of about 755,676 (359)

anesthetic: nested sampling visualisation [PDF]

Journal of Open Source Software, 2019, 4(37), 1414, 2019
anesthetic is a Python package for processing nested sampling runs, and will be useful for any scientist or statistician who uses nested sampling software. anesthetic unifies many existing tools and techniques in an extensible framework that is intuitive for users familiar with the standard Python packages, namely NumPy, SciPy, Matplotlib and pandas.
arxiv   +1 more source

Shared structural mechanisms of general anesthetics and benzodiazepines

Nature, 2020
Most general anaesthetics and classical benzodiazepine drugs act through positive modulation of γ-aminobutyric acid type A (GABA A ) receptors to dampen neuronal activity in the brain 1 – 5 .
Jeong Joo Kim, A. Gharpure, J. Teng, Y. Zhuang, R. Howard, Shaotong Zhu, C. Noviello, R. M. Walsh, E. Lindahl, R. Hibbs   +9 more
semanticscholar   +1 more source

Effects of Anesthetics on Barrier Tissue Function

Journal of Immunology Research, 2019
Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are ...
Fujing Wang, Yanhui Li, Changlei Cui, Zhaoping Xue, Haichun Ma   +4 more
doaj   +1 more source

Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application

OncoTarget, 2016
Anesthetics are unavoidable to colorectal cancer (CRC) patients who underwent surgical treatment. Thus, the molecular mechanisms underlying the role of the intravenous anesthetics in CRC metastasis are still unclear.
Fengliu Deng, Mingwen Ouyang, Xiaofei Wang, Xue-qing Yao, Yeming Chen, Taoliangshan Tao, Xuegang Sun, Lijun Xu, Jing Tang, Liang Zhao   +9 more
semanticscholar   +1 more source

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

Nature Communications, 2023
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami, Md Mahfuzur Rahman, Jinfeng Teng, Ryan E. Hibbs   +3 more
doaj   +1 more source

Common anesthetic molecules prefer to partition in liquid disorder phase domain in a composite multicomponent membrane [PDF]

Phys. Rev. E 98, 012409 (2018), 2018
Despite a vast clinical application of anesthetics, the molecular level of understanding of general anesthesia is far from our reach. Using atomistic molecular dynamics simulation, we study the effects of common anesthetics: ethanol, chloroform and methanol in the fully hydrated symmetric multicomponent lipid bilayer membrane comprising of an ...
arxiv   +1 more source

Effect of preoperative dexmedetomidine nebulization on the hemodynamic response to laryngoscopy and intubation: a randomized control trial [PDF]

Korean Journal of Anesthesiology, 2021
Background Dexmedetomidine, an alpha-2 agonist, has been used for attenuation of hemodynamic response to laryngoscopy but not through the nebulized route.
Satyajeet Misra, Bikram Kishore Behera, Jayanta Kumar Mitra, Alok Kumar Sahoo, Sritam Swarup Jena, Anand Srinivasan   +5 more
doaj   +1 more source

Managing Opioid-Tolerant Patients in the Perioperative Surgical Home. [PDF]

, 2016
Management of acute postoperative pain is important to decrease perioperative morbidity and improve patient satisfaction. Opioids are associated with potential adverse events that may lead to significant risk.
Baratta, Jaime L., Schwenk, Eric S., Viscusi, Eugene R., Wenzel, John T.   +3 more
core   +3 more sources

Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]

, 2020
Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv   +1 more source

Edge AI-Based Vein Detector for Efficient Venipuncture in the Antecubital Fossa [PDF]

, 2023
Assessing the condition and visibility of veins is a crucial step before obtaining intravenous access in the antecubital fossa, which is a common procedure to draw blood or administer intravenous therapies (IV therapies). Even though medical practitioners are highly skilled at intravenous cannulation, they usually struggle to perform the procedure in ...
arxiv   +1 more source