Results 41 to 50 of about 736,541 (316)
On the action potential as a propagating density pulse and the role of anesthetics [PDF]
Biophys. Rev. Letters 2 (2007) 57-78, 2006 The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory. Particularly striking is the finding of reversible heat changes, thickness and phase changes of the membrane during ...
arxiv +1 more source
Neuroprotective effects of intravenous anesthetics: a new critical perspective.
Current pharmaceutical design, 2014 Perioperative cerebral damage can result in various clinical sequela ranging from minor neurocognitive deficits to catastrophic neurological morbidity with permanent impairment and death.
F. Bilotta +4 more
semanticscholar +1 more source
The thermodynamics of lipid ion channel formation in the absence and presence of anesthetics. BLM experiments and simulations [PDF]
Soft Matter, 2009, 5: 3319-3330, 2009 It is known that lipid membranes become permeable in their melting regime. In microscopic conductance measurements on black lipid membranes one finds that conduction takes place via quantized events closely resembling those reported for protein ion channels. Here, we present data of ion currents through black lipid membranes in the presence and absence
arxiv +1 more source
The Effect of Intravenous Anesthetics on Ischemia-Reperfusion Injury
BioMed Research International, 2014 The effects of intravenous anesthetics on ischemia-reperfusion injury (IRI) have been investigated in both animals and clinical studies. The protective effects and the dosages of the intravenous anesthetics on IRI were discussed in this paper.
A. Eroğlu
semanticscholar +1 more source
BMC Anesthesiology, 2019 Background To compare surgical field visibility between patients given propofol/remifentanil (PR) or desflurane/remifentanil (DR) anesthesia. Methods A total of 80 adult patients undergoing middle ear microsurgery due to cholesteatoma otitis media with ...
Xia Yuan +3 more
doaj +1 more source
The free energy of biomembrane and nerve excitation and the role of anesthetics [PDF]
BBA - Biomembranes 1860 (2018) 2145-2153, 2018 In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference necessary to induce a phase transition in the nerve membrane.
arxiv +1 more source
BMC Medical Imaging, 2012 Background Although general anesthesia is widely used in the surgical arena, the mechanisms by which general anesthetics act remain unclear. We previously described alterations in gene expression ratios in hepatic tissue taken from rats treated with ...
Tajima Tomoyuki +3 more
doaj +1 more source
Systemic immune effects of anesthetics and their intracellular targets in tumors
Frontiers in Medicine, 2022 According to the result released by the World Health Organization (WHO), non-communicable diseases have occupied four of the top 10 current causes for death in the world.
Ting Luan +9 more
doaj +1 more source
Anesthesia and Analgesia, 2013 The use of local anesthetics to reduce acute postoperative pain has a long history, but recent reports have not been systematically reviewed. In addition, the need to include only those clinical studies that meet minimum standards for randomization and ...
Antje M. Barreveld +4 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Febrile infection related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus with immune dysregulation as a potential pathologic mechanism. Despite promising results from second‐line immunomodulators, approximately 30% remain refractory to treatment.
Kristen S. Fisher +5 more
wiley +1 more source