Results 41 to 50 of about 310,289 (342)

A randomized controlled prospective study comparing a low dose bupivacaine and fentanyl mixture to a conventional dose of hyperbaric bupivacaine for cesarean section

open access: yesSaudi Journal of Anaesthesia, 2015
Context: Hormonal and mechanical factors make obstetric patients need strict dose calculations of local anesthetics intrathecally for spinal anesthesia.
Himabindu Gandam Venkata   +4 more
doaj   +1 more source

Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs

open access: yesFrontiers in Pharmacology, 2022
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng   +5 more
doaj   +1 more source

Effects of Anesthesia and Anesthetic Techniques on Metastasis of Lung Cancers: A Narrative Review

open access: yesCancer Management and Research, 2022
Zhenghuan Song, Jing Tan Department of Anesthesiology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People’s Republic of ...
Song Z, Tan J
doaj  

Effect of Anesthetics on Red Blood Cell Membranes

open access: yesОбщая реаниматология, 2007
Objective: to comparatively analyze the effect of anesthetics on red blood cell membranes in whole blood and its suspension.Materials and methods. The blood sampled from healthy donors was studied.
P. Yu. Alekseyeva   +8 more
doaj   +1 more source

Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]

open access: yes, 2009
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.   +2 more
core   +2 more sources

Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness

open access: yesFront. Neural Circuits, 2017
There has been controversy regarding the precise mechanisms of anesthetic-induced unconsciousness, with two salient approaches that have emerged within systems neuroscience.
G. Mashour, A. Hudetz
semanticscholar   +1 more source

Direct Current Auditory Evoked Potentials During Wakefulness, Anesthesia, and Emergence from Anesthesia [PDF]

open access: yes, 2001
Direct current auditory evoked potentials (DC-AEPs) are a sensitive indicator of depth of anesthesia in ani-mals. However, they have never been investigated in humans. To assess the potential usefulness of DC-AEPs as an indicator of anesthesia in humans,
Bauer, Herbert   +5 more
core   +1 more source

Local anesthetics: hydrophilic and hydrophobic pathways for the drug- receptor reaction

open access: yesThe Journal of General Physiology, 1977
The properties of Na channels of the node of Ranvier are altered by neutral, amine, and quaternary local anesthetic compounds. The kinetics of the Na currents are governed by a composite of voltage- and time- dependent gating processes with voltage- and ...
B. Hille
semanticscholar   +1 more source

Anesthetic neurotoxicity in the developing brain: an update on the insights and implications for fetal surgery [PDF]

open access: yesAnesthesia and Pain Medicine
This review describes an in-depth analysis of the neurotoxicity associated with the anesthetic agents used during fetal surgery, intending to highlight the importance of understanding the effects of general anesthetics on the developing brain ...
Denise Cinquegrana   +6 more
doaj   +1 more source

Propofol Improved Glucose Tolerance Associated with Increased FGF-21 and GLP-1 Production in Male Sprague-Dawley Rats

open access: yesMolecules, 2020
Anesthetics, particularly volatile anesthetics, have been shown to impair glucose metabolism and cause hyperglycemia, closely linking them with mortality and morbidity as related to surgery.
Chih-Cheng Wu   +8 more
doaj   +1 more source

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