Results 41 to 50 of about 305,020 (386)
Introduction:Â Compared to ordinary people, addicts usually have a lower pain threshold. The current work attempts to compare the performance of local analgesia with lidocaine among opium addicts and non-addicts.
Alireza Majidi+2 more
doaj +1 more source
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.+2 more
core +2 more sources
Anesthetic agents are often used in fish experiments to reduce the stress and struggle and to improve animal welfare. The present study aimed to determine the optimal doses and serum minimum effective concentration (MEC) of tricaine methanesulfonate (MS ...
Tirawat Rairat+5 more
doaj +1 more source
USE OF INHALANT ANESTHETICS IN THREE SNAKE SPECIES [PDF]
Different snake species respond differently to various anesthetic agents. Hence, an anesthetic procedure developed for one species cannot necessarily be safely transferred to another species.
Blouin-Demers, Gabriel+4 more
core +2 more sources
General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels
General anesthetics are indispensable for effective clinical care. Although, the mechanism of action of general anesthetics remains controversial, lipid bilayers and proteins have been discussed as their targets.
J. Kishikawa+7 more
semanticscholar +1 more source
Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics
Cancer is one of the leading causes of death worldwide. There are only limited treatment strategies that can be applied to treat cancer, including surgical resection, chemotherapy, and radiotherapy, but these have only limited effectiveness. Developing a
King-Chuen Wu+3 more
doaj +1 more source
Background and Aim: The postoperative shivering is one of the common complications of anesthesia, which can cause increased systemic blood pressure, oxygen consumption, intra optical pressure and heart rate in patients.
Maryam Kheirandish+3 more
doaj +2 more sources
Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng+5 more
doaj +1 more source
Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran+4 more
core +3 more sources
There has been controversy regarding the precise mechanisms of anesthetic-induced unconsciousness, with two salient approaches that have emerged within systems neuroscience.
G. Mashour, A. Hudetz
semanticscholar +1 more source