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Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study

open access: yesArchives of Academic Emergency Medicine, 2018
Introduction: Compared to ordinary people, addicts usually have a lower pain threshold. The current work attempts to compare the performance of local analgesia with lidocaine among opium addicts and non-addicts.
Alireza Majidi   +2 more
doaj   +1 more source

Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]

open access: yes, 2009
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.   +2 more
core   +2 more sources

Determination of Optimal Doses and Minimum Effective Concentrations of Tricaine Methanesulfonate, 2-Phenoxyethanol and Eugenol for Laboratory Managements in Nile Tilapia (Oreochromis niloticus)

open access: yesAnimals, 2021
Anesthetic agents are often used in fish experiments to reduce the stress and struggle and to improve animal welfare. The present study aimed to determine the optimal doses and serum minimum effective concentration (MEC) of tricaine methanesulfonate (MS ...
Tirawat Rairat   +5 more
doaj   +1 more source

USE OF INHALANT ANESTHETICS IN THREE SNAKE SPECIES [PDF]

open access: yes, 2000
Different snake species respond differently to various anesthetic agents. Hence, an anesthetic procedure developed for one species cannot necessarily be safely transferred to another species.
Blouin-Demers, Gabriel   +4 more
core   +2 more sources

General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels

open access: yesPLoS ONE, 2018
General anesthetics are indispensable for effective clinical care. Although, the mechanism of action of general anesthetics remains controversial, lipid bilayers and proteins have been discussed as their targets.
J. Kishikawa   +7 more
semanticscholar   +1 more source

Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics

open access: yesBiomedicines, 2022
Cancer is one of the leading causes of death worldwide. There are only limited treatment strategies that can be applied to treat cancer, including surgical resection, chemotherapy, and radiotherapy, but these have only limited effectiveness. Developing a
King-Chuen Wu   +3 more
doaj   +1 more source

The Evaluation Between The Impact Of Using Isoflurane And Propofol On Shivering Among Patients Undergoing Vitrectomy Surgery

open access: yesپیاورد سلامت, 2016
Background and Aim: The postoperative shivering is one of the common complications of anesthesia, which can cause increased systemic blood pressure, oxygen consumption, intra optical pressure and heart rate in patients.
Maryam Kheirandish   +3 more
doaj   +2 more sources

Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs

open access: yesFrontiers in Pharmacology, 2022
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng   +5 more
doaj   +1 more source

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

open access: yes, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran   +4 more
core   +3 more sources

Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness

open access: yesFront. Neural Circuits, 2017
There has been controversy regarding the precise mechanisms of anesthetic-induced unconsciousness, with two salient approaches that have emerged within systems neuroscience.
G. Mashour, A. Hudetz
semanticscholar   +1 more source

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