When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies
Abstract Protein‐losing enteropathy (PLE) is a rare condition that is characterized by loss of plasma protein in the intestines leading to hypoproteinemia with subsequent peripheral edema and possibly anasarca. The pathophysiology of PLE varies depending on the etiology and involves either intestinal mucosal injury or lymphatic system alterations ...
Natalie Jennings +7 more
wiley +1 more source
Caracterización molecular de la deficiencia del factor I en dos familias españolas [PDF]
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina. Departamento de Bioquímica.
Ponce Castro, Isabel María
core +1 more source
Abstract Approximately 8% of pregnant people report being allergic to penicillin, yet most of these patients are not truly allergic, either because their allergy has waned or was misdiagnosed in the first place. Penicillin allergy testing can distinguish those who are at risk for reaction to penicillin from those with no or minimal risk.
Society for Maternal‐Fetal Medicine (SMFM) +8 more
wiley +1 more source
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source
Eficacia y seguridad de la profilaxis a corto plazo con andrógenos atenuados y/o concentrado plasmático de C1 inhibidor en la relación de procedimientos odontoestomatológicos, maxilofaciales y otorrinolaringológicos en pacientes con angiodema hereditario por déficit de la proteína inhibidor de la C1 Esterasa funcionalmente activa [PDF]
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Medicina.
Jurado Palomo, Jesús
core
Codfish Oral Immunotherapy in Children Aged 2–10: Randomized Placebo‐Controlled Study
Codfish OIT significantly increased desensitization in children with fish allergy (43% vs. 11% placebo, p = 0.003), with 69% achieving 10‐fold threshold increases versus 26% in placebo (p = 0.0003). Sustained unresponsiveness remained limited (23% vs. 9%, p = 0.332). Treatment demonstrated acceptable safety with predominantly mild reactions and reduced
Agnes Sze‐yin Leung +9 more
wiley +1 more source
Stratified medicine: methods for evaluation of predictive biomarkers [PDF]
Background: Stratified medicine was defined as the use of biomarkers to select patients more likely to respond to a treatment or experience an adverse event.
Malottki, Kinga
core
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Over diagnosis of bradykinin angioedema in patients treated with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. [PDF]
Douillard M +7 more
europepmc +1 more source
This systematic review maps core outcome sets and harmonisation efforts in allergy and clinical immunology. Despite shared priorities such as quality of life and symptoms, substantial gaps and methodological inconsistencies remain, underscoring the need for broader coverage and standardised outcome measurement to improve comparability and clinical ...
Anastasia Demidova +45 more
wiley +1 more source

