Results 111 to 120 of about 616 (213)

Supply and Demand in the Mathematics of Rare Disease Drug Development: Why Choosing the Right Model Is Crucial

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Clinical trials for rare diseases face a fundamental mathematical challenge that conventional randomized controlled trial (RCT) designs cannot overcome. With approximately 95% of the estimated 10,000–16,000 rare diseases lacking approved therapies, and drug development programs failing at rates exceeding 75% in non‐oncology indications, the ...
Marshall L. Summar, Janet Woodcock
wiley   +1 more source

Hereditary angioedema

Medicina Clínica (English Edition), 2015
Teresa, Caballero Molina, María, Pedrosa Delgado, Carmen, Gómez Traseira   +2 more
openaire   +3 more sources

Delayed urticaria during treatment with anti‐CGRP monoclonal antibodies in migraine

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1193-1199, May 2026.
Abstract Objective To characterize clinical presentation and management of urticaria associated with calcitonin gene‐related peptide (CGRP) ‐targeting monoclonal antibodies (mAbs) for migraine prophylaxis. Background CGRP‐targeting mAbs are effective in migraine prophylaxis, but have been associated with hypersensitivity reactions, including urticaria.
Christoph T. Berger, Federico Burguet Villena, Severin B. Vogt, Lukas Heydrich, Karin Hartmann, Athina Papadopoulou   +5 more
wiley   +1 more source

Angioedema Histaminérgico Recidivante Idiopático: características diferenciales [PDF]

Introducción: El diagnóstico del AE histaminérgico recidivante supone un desafío en la práctica clínica diaria por su similitud con otras formas de AE y la ausencia de biomarcadores diagnósticos diferenciales.
Laínez Nuez, Ana
core  

Hereditary angioedema

Canadian Medical Association Journal
Uminski, Kelsey, Betschel, Stephen, Goodyear, Dawn   +2 more
  +5 more sources

Idiopathic non-histaminergic acquired angioedema: a case series and discussion of published clinical trials [PDF]

A Berry, A Du-Thanh, A Frenkel, A Websky von, AB Ozturk, AP Kaplan, AP Kaplan, AP Kaplan, C Faisant, C Faisant, C Gravante, C Oschatz, C Saule, C Wintenberger, D Franzen, DW MacGlashan Jr, F Citarella, H Farkas, I Corso Del, IT Harvima, J Azofra, J Shroba, JP Munoz, K Bork, L Tengborn, LA Beck, LC Zingale, M Cicardi, M Cicardi, M Mansi, M Maurer, M Metz, MC Stahl, MF Sands, O Şener, OM Hakansson, P Gonzalez, RA Thompson, S Ghazan-Shahi, S Guillen-Aguinaga, TB Dy, TC Theoharides, V Montinaro, W Aberer, World Medical Association   +44 more
core   +1 more source

Editorial: Bradykinin and histamine mediated angioedema. [PDF]

Front Allergy
Patil AD, Peter J, Rudenko M.
europepmc   +1 more source

Qualidade de vida em pacientes com angioedema hereditário [PDF]

Orientador: Prof. Dr. Nelson Rosário FilhoCoorientador (a): Profa. Dra. Lilian Pereira FerrariTese (doutorado) - Universidade Federal do Paraná, Ciências da Saúde, Programa de Pós-Graduação em Medicina Interna e Ciências da Saúde.
Kruk, Tatielly
core  

Isolated Mast Cell–Mediated Angioedema: Clinically Different but Endotypically Similar to Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, Volume 56, Issue 5, Page 562-564, May 2026.
Thomas Buttgereit, Claudia Hayford, Carolina Vera Ayala, Sherezade Moñino‐Romero, Yi‐Kui Xiang, Pavel Kolkhir, Carolin Steinert, Denise Freier, Markus Magerl, Jörg Scheffel, Karsten Weller   +10 more
wiley   +1 more source

Type II hereditary angioedema with an apparently de novo SERPING1 mutation in China: A case report and family screening. [PDF]

Medicine (Baltimore)
Guan Z, Cai L, Li Y, She X, Ye B, Wang X.   +5 more
europepmc   +1 more source