Results 121 to 130 of about 801,916 (360)

Expression and purification of bioactive, low-endotoxin recombinant human vitronectin

open access: yesBioTechniques, 2014
The secreted adhesive glycoprotein vitronectin (VTN) is a multifunctional component of plasma and the extracellular matrix. A high-yielding, inexpensive, low endotoxin source of bioactive recombinant human vitronectin (rhVTN) is highly desirable for in ...
Michael M. Halford   +2 more
doaj   +1 more source

Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]

open access: yes, 2018
Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara   +5 more
core   +2 more sources

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Inhibition of Tumor Growth and Angiogenesis by Soluble EphB4

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
EphB receptors and their ephrinB ligands play a key role in the formation of a regular vascular system. Recent studies have also shown the involvement of Eph/ephrin interactions in malignant tumor progression and angiogenesis.
Georg Martiny-Baron   +6 more
doaj   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

open access: yesFEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang   +5 more
wiley   +1 more source

Angiogenesis: an update.

open access: yesHistology and histopathology, 1994
Angiogenesis is the neovascularization or formation of new blood vessels from the established microcirculation. It is particularly important and indispensable in a large number of normal and pathological processes during pre- and post-natal life, including neoplasia, inflammation, wound repair and collaterization in response to ischemic stimuli.
Díaz-Flores, Lucio   +2 more
openaire   +2 more sources

Tumor Angiogenesis [PDF]

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 2000
In order to grow beyond minimal size and to metastasize, tumors need to induce the growth of new blood vessels (angiogenesis). Whereas in normal tissues, vascular quiescence is maintained by the dominant influence of endogenous angiogenesis inhibitors over angiogenic stimuli, tumor angiogenesis is induced by increased secretion of angiogenic factors ...
openaire   +2 more sources

Angiogenesis: A Model of Cell Differentiation [PDF]

open access: yes, 2000
Angiogenesis is the formation of blood vessels, and is of great importance in the growth of tumours. Attempts have been made to desgin experiments in petri-dishes that mimic the 'Conditions of tumour growth. The first of the experiments is the 'matrigel'
Hinch, R.
core  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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