Results 31 to 40 of about 952,689 (432)
iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
Nature Communications, 2019 The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre ...
Macarena Fernández-Chacón +6 more
doaj +1 more source
Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]
, 2004 BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
Bhardwaj, S +9 more
core +1 more source
Cell Death and Disease, 2021 Dental pulp stem cells (DPSC) are capable of differentiating into vascular endothelial cells. Although the capacity of vascular endothelial growth factor (VEGF) to induce endothelial differentiation of stem cells is well established, mechanisms that ...
Zhaocheng Zhang +3 more
doaj +1 more source
Angiogenesis and Endometriosis [PDF]
Obstetrics and Gynecology International, 2013 A comprehensive review was performed to survey the role of angiogenesis in the pathogenesis of endometriosis. This is a multifactorial disease in which the development and maintenance of endometriotic implants depend on their invasive capacity and angiogenic potential. The peritoneal fluid of patients with endometriosis is a complex suspension carrying
Robert N. Taylor +2 more
openaire +4 more sources
MiR675-5p acts on HIF-1α to sustain hypoxic responses: A new therapeutic strategy for glioma [PDF]
, 2016 Hypoxia is a common feature in solid tumours. In glioma, it is considered the major driving force for tumour angiogenesis and correlates with enhanced resistance to conventional therapies, increased invasiveness and a poor prognosis for patients. Here we
Alessandro, Riccardo +10 more
core +2 more sources
Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.
New England Journal of Medicine, 1991 BACKGROUND Experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis, which may also permit metastasis.
N. Weidner +3 more
semanticscholar +1 more source
The statistical theory of the angiogenesis equations [PDF]
arXiv, 2022 Angiogenesis is a multiscale process by which a primary blood vessel issues secondary vessel sprouts that reach regions lacking oxygen. Angiogenesis can be a natural process of organ growth and development or a pathological induced by a cancerous tumor.
arxiv
Positivity preserving high order schemes for angiogenesis models [PDF]
International Journal of Nonlinear Sciences and Numerical
Simulation 2021, 2020 Hypoxy induced angiogenesis processes can be described coupling an integrodifferential kinetic equation of Fokker-Planck type with a diffusion equation for the angiogenic factor. We propose high order positivity preserving schemes to approximate the marginal tip density by combining an asymptotic reduction with weighted essentially non oscillatory and ...
arxiv +1 more source
Prioritization and functional validation of target genes from single-cell transcriptomics studies
Communications Biology, 2023 Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional validation, it
Liliana Sokol +12 more
doaj +1 more source
Well posedness of an angiogenesis related integrodifferential diffusion model [PDF]
Applied Mathematical Modelling 40 (2016) 5560-5575, 2016 We prove existence and uniqueness of nonnegative solutions for a nonlocal in time integrodifferential diffusion system related to angiogenesis descriptions. Fundamental solutions of appropriately chosen parabolic operators with bounded coefficients allow us to generate sequences of approximate solutions.
arxiv +1 more source