Results 31 to 40 of about 519,126 (297)

The von Willebrand factor stamps plasmatic extracellular vesicles from glioblastoma patients

Scientific Reports, 2021
Glioblastoma is a devastating tumor of the central nervous system characterized by a poor survival and an extremely dark prognosis, making its diagnosis, treatment and monitoring highly challenging.
Quentin Sabbagh, Gwennan André-Grégoire, Carolina Alves-Nicolau, Aurélien Dupont, Nicolas Bidère, Emmanuel Jouglar, Laëtitia Guével, Jean-Sébastien Frénel, Julie Gavard   +8 more
doaj   +1 more source

Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells [PDF]

, 2021
Zheng Fan, Guillermo Turiel, Raphaela Ardicoglu, Moheb Ghobrial, Evi Masschelein, Tea Kocijan, Jing Zhang, Ge Tan, Gillian Fitzgerald, Tatiane Gorski, Abdiel Alvarado-Diaz, Paola Gilardoni, Christopher M. Adams, Bart Ghesquière, Katrien De Bock   +14 more
openalex   +1 more source

Therapeutic angiogenesis

British Journal of Surgery, 2006
Still a long way ...
S A, Choksy, P, Chan
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Mapping diurnal variations in choroidal sublayer perfusion in patients with idiopathic epiretinal membrane: an optical coherence tomography angiography study

International Journal of Retina and Vitreous, 2019
Background Optical coherence tomography angiography (OCTA) is a non-invasive tool for imaging and quantifying the choroidal vasculature and perfusion state. In this index study, OCTA was used to investigate diurnal changes in choroidal sublayer perfusion
Felix Rommel, Fynn Siegfried, Jan A. M. Sochurek, Matthias Rothe, Max P. Brinkmann, Maximilian Kurz, Michelle Prasuhn, Salvatore Grisanti, Mahdy Ranjbar   +8 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells

Communications Biology
Endothelial cells (ECs) are highly glycolytic, but whether they generate glycolytic intermediates via gluconeogenesis (GNG) in glucose-deprived conditions remains unknown.
Pauline de Zeeuw, Lucas Treps, Melissa García-Caballero, Ulrike Harjes, Joanna Kalucka, Carla De Legher, Katleen Brepoels, Kristel Peeters, Stefan Vinckier, Joris Souffreau, Ann Bouché, Federico Taverna, Jonas Dehairs, Ali Talebi, Bart Ghesquière, Johan Swinnen, Luc Schoonjans, Guy Eelen, Mieke Dewerchin, Peter Carmeliet   +19 more
doaj   +1 more source

Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway

FEBS Open Bio, 2023
Identifying novel targets that control both tumorigenesis and angiogenesis can aid in developing a more potent anti‐angiogenic therapeutic strategy. We previously reported that reduction of FRG1 is associated with increased p38‐MAPK signaling in prostate
Bratati Mukherjee, Pratush Brahma, Talina Mohapatra, Saurabh Chawla, Manjusha Dixit   +4 more
doaj   +1 more source

Poststroke Angiogenesis, Con [PDF]

Stroke, 2015
Angiogenesis, the regrowth of new blood vessels, occurs after stroke1 and thus raises hopes that this regeneration is beneficial for patients with stroke. There is no doubt, that the restoration of blood supply, providing oxygen and nutrients to the ischemic brain tissue, is beneficial for stroke recovery.
J. Adamczak, M. Hoehn
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source