Results 151 to 160 of about 182,387 (331)

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

Advanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong, Wenao Liao, Lingcong Xu, Niezhenghao He, Ke Xu, Caiyuan Liu, Fei Wang, Wei Zhang, Jiang Hu, Haowen Cui   +9 more
wiley   +1 more source

Modelling Tumor-induced Angiogenesis: Combination of Stochastic Sprout Spacing and Sprout Progression

Journal of Biomedical Physics and Engineering, 2017
Background: Angiogenesis initiated by cancerous cells is the process by which new blood vessels are formed to enhance oxygenation and growth of tumor.
Hosseini F., Naghavi N.
doaj  

Administration of VEGF receptor tyrosine kinase inhibitor increases VEGF production causing angiogenesis in human small-cell lung cancer xenografts

, 1992
Takaaki Sasaki
openalex   +2 more sources

Arginine-rich Anti-vascular Endothelial Growth Factor Peptides Inhibit Tumor Growth and Metastasis by Blocking Angiogenesis [PDF]

, 2000
Donggoo Bae, Yong-Song Gho, Woong Yoon, Chi‐Bom Chae   +3 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Comparison of anti-inflammatory and anti-angiogenic effects of JAK inhibitors in IL-6 and TNFα-stimulated fibroblast-like synoviocytes derived from patients with RA

Scientific Reports
Rheumatoid arthritis (RA) involves synovial tissue proliferation, inflammation, and angiogenesis, and contributes to joint destruction. Angiogenesis is a key therapeutic target for the treatment of RA, and Janus kinase (JAK) inhibitors have emerged as a ...
Yoshihito Suda, Kemmei Ikuta, Shinya Hayashi, Kensuke Wada, Kensuke Anjiki, Tomoyuki Kamenaga, Masanori Tsubosaka, Yuichi Kuroda, Naoki Nakano, Toshihisa Maeda, Ken Tsumiyama, Tomoyuki Matsumoto, Ryosuke Kuroda, Tsukasa Matsubara   +13 more
doaj   +1 more source

Angiogenesis Inhibitors in Small Cell Lung Cancer. [PDF]

Front Oncol, 2021
Montanino A, Manzo A, Carillio G, Palumbo G, Esposito G, Sforza V, Costanzo R, Sandomenico C, Botti G, Piccirillo MC, Cascetta P, Pascarella G, La Manna C, Normanno N, Morabito A.   +14 more
europepmc   +1 more source

Anticancer effects of chemoembolization using microspheres of an angiogenesis inhibitor (TNP-470) in rabbits bearing VX-2 carcinoma.

, 1992
Hiroaki Okada, Shigeru Kamei, Toshio Yoshioka, Yayoi Inoue, Yasuaki Ogawa, Hajime Toguchi   +5 more
openalex   +2 more sources

Inorganic Nanomaterials Meet the Immune System: An Intricate Balance

Advanced Healthcare Materials, EarlyView.
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli, Marco Gargaro, Giuliana Drava, Valerio Voliani   +3 more
wiley   +1 more source

Injectable 2D‐MoS2‐integrated Bioadhesive Hydrogel as Photothermal‐Derived and Drug‐Delivery Implant for Colorectal Cancer Therapy

Advanced Healthcare Materials, EarlyView.
An injectable, adhesive hydrogel integrating 2D‐MoS2 and 5‐fluorouracil (AlgNB/MoS2/5‐FU) is developed for near‐infrared‐triggered photothermal therapy and localized drug delivery. The adhesive hydrogel demonstrates superior tumor anchoring, efficient photothermal conversion, and synergistic inhibition of colorectal cancer progression, offering a ...
Xiaojun Long, Jiawei Wang, Huijuan Wang, Kepeng Hu, Wei Zhang, Weiming Lin, Chao Fang, Kui Cheng, Zhangfa Song   +8 more
wiley   +1 more source