Results 131 to 140 of about 215,305 (295)

PKD1 3D Structure Model and Docking Studies for New PKD Inhibitors [PDF]

, 2013
Protein kinase Ds (PKDs) are diacylglycerol (DAG)-regulated serine/threonine protein kinases. In intact cells, PKDs are key mediators in cellular processes pertaining to multiple diseases, including cancer, heart diseases, angiogenesis and immune ...
Xu, Qi
core  

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer. [PDF]

Cochrane Database Syst Rev, 2023
Gaitskell K, Rogozińska E, Platt S, Chen Y, Abd El Aziz M, Tattersall A, Morrison J.   +6 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Angiogenesis Inhibitors and Cytotoxic Compounds [PDF]

, 2007
Marine microorganisms have been recognized as a promising source for the production of bioactive secondary metabolites. However, marine actinomycetes have been largely ignored until recently.1 To search for new bioactive marine natural products, we have ...
신희재, 이희승
core  

Current Status of Angiogenesis Inhibitors as Second-Line Treatment for Unresectable Colorectal Cancer. [PDF]

Cancers (Basel), 2023
Otsu S, Hironaka S.
europepmc   +1 more source

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

The therapeutic potential of angiogenesis inhibitors [PDF]

, 2007
В статье проанализированы современные представления о клеточных и молекулярных механизмах ангиогенеза в норме и при росте опухоли. Основное внимание уделено ангиогенным факторам, их эндогенным ингибиторам, интегринам и матриксным металлопротеиназам ...
Фильченков, А.А.
core  

Meniscus‐Guided Interfacial Ring‐by‐Ring Assembly for In Situ Fabrication of Tubular Hydrogels

Advanced Materials, EarlyView.
A tubular hydrogel fabrication method leveraging the meniscus effect at the oil‐water interface is presented. UV irradiation across the concave surface of the photocurable hydrogel precursor induces the formation of ring‐like hydrogel structures. Sequential ring‐by‐ring assembly within microchannels enables the construction of arteriole‐scale hydrogel ...
Yuki Kamiya, Yingzhe Wang, Keisuke Morishima   +2 more
wiley   +1 more source

Anti(angiogenic) food components: can be a major source of bias in the investigation of angiogenesis inhibitors. [PDF]

Ann Transl Med, 2023
Rastmanesh R, Bowirrat A, Gupta A, Gilley E, Blum K.   +4 more
europepmc   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source