Results 111 to 120 of about 215,305 (295)

New Angiogenesis Inhibitors from Marine-Derived Actinomycetes [PDF]

, 2009
Marine microbial natural products continue to represent an important source of novel compounds for the development of new therapeutic agents. As part of our ongoing research to isolate novel angiogenesis inhibitors, we have focused considerable attention
신희재, 이희승, 권호정
core  

Comparison of primary outcomes for bevacizumab versus other angiogenesis inhibitors. [PDF]

, 2016
Comparison of primary outcomes for bevacizumab versus other angiogenesis inhibitors.
Meng Zhao (54299), Dan Xing (128154), Jie Wang (16762), Yang Yang (45629), Yawei Wang (1445449)   +4 more
core   +1 more source

FAK inhibitor suppresses ovarian cancer growth by inhibiting tumor angiogenesis

Cancer Cell International
Background Ovarian cancer, the second deadliest gynecological malignancy, necessitates the identification of novel therapeutic targets. Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, has emerged as a promising target for ovarian cancer ...
Jingtian Shen, Zhiru Su, Yihan Shan, Ying Wang, Yi Meng, Zhiling Li, Shuping Miao, Jinyi Zhang, Xiaojian Yan   +8 more
doaj   +1 more source

3D‐Printable, Biodegradable, and Conductive/Piezoionic Hydrogel ‘E‐Skin’ With Robust Antibacterial Properties for Wound Healing and Wireless Human‐Machine Interface Sensing

Advanced Functional Materials, EarlyView.
A multifunctional MXene‐integrated GelMA/alginate hydrogel reinforced with TEMPO‐modified nanocellulose is engineered via dynamic covalent, ionic, and hydrogen bonding. The resulting piezoelectric, adhesive, antimicrobial, and 3D‐printable patch enables motion sensing and accelerates wound healing by promoting keratinocyte migration and collagen ...
Myoungjoon Jeon, Sayan Deb Dutta, Md. Moniruzzaman, Jeong Man An, Youjin Seol, Gyuhan Son, Sung Ha Jo, Hyun Chang Jung, Beom‐Soo Shin, Jongsung Kim, Yong‐kyu Lee, Ki‐Taek Lim   +11 more
wiley   +1 more source

Recent progress in the exploitation of anti-cancer small molecules targeting angiogenesis

Journal of Enzyme Inhibition and Medicinal Chemistry
Angiogenesis is pivotal for cancer growth and metastasis, as tumours rely on new blood vessels to progress and spread. Antiangiogenic drugs represent a crucial therapeutic strategy that combats cancer by both obstructing the development of new blood ...
Ying Zheng, Hao Qiu, Ke Zhang, Xiang Ji, Mingxia Song, Xianqing Deng   +5 more
doaj   +1 more source

Angiogenesis inhibitors for metastatic colorectal cancer. [PDF]

Transl Cancer Res, 2023
Pfeiffer P, Liposits G, Taarpgaard LS.
europepmc   +1 more source

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

‐Y078, overcomes resistance to tumor angiogenesis inhibitors [PDF]

, 2018
Tumor angiogenesis inhibition is one of the most potent strategies in cancer chemotherapy. From past clinical studies, inhibition of the vascular endothelial growth factor pathway successfully treats malignant tumors. However, vascular endothelial growth
Tanaka, Masamitsu, Taichi Yoshida, Shunsuke Sugiyama, Inoue, Masahiro, Iwabuchi, Yoshiharu, Shimazu, Kazuhiro, Uehara, Yoshihiko, Shibata, Hiroyuki, Hiroshi Nanjyo, Sei Kuriyama, Nanjyo, Hiroshi, Masahiro Inoue, Yoshihiko Uehara, Masatomo Miura, Yoshida, Taichi, Hiroyuki Shibata, Masamitsu Tanaka, Miura, Masatomo, Fukuda, Koji, Koji Fukuda, Daiki Taguchi, Kuriyama, Sei, Yoshiharu Iwabuchi, Sugiyama, Shunsuke, Kazuhiro Shimazu, Taguchi, Daiki   +25 more
core   +2 more sources

Mimetic Core‐Sheath Silk Sutures with Superior‐Strength for Pain Management, Anti‐Infection and Wound Healing

Advanced Healthcare Materials, EarlyView.
ABSTRACT Sutures are crucial for tissue approximation and wound healing. Besides their strength limits requirement, they often fail to effectively address complications like infection and pain. Inspired by natural silk's “core‐sheath” structure, our suture features a wet‐spun core of n zinc‐fortified silk fibroin fibers (RSF‐Zn2+) after drawing with ...
Yi Peng, Kai Ma, Xiaoxiao Li, Xiaozhuo Wu, Yuezhou Zhang, Ying Luo, Chenxing Zhang, Wen Zhong, Chunjing Yu, Lin Lu, Malcolm Xing, Guozhong Lyu   +11 more
wiley   +1 more source

Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3).

PLoS ONE, 2014
Angiogenesis is the formation of new blood vessels form pre-existing vasculature whose contribution to inflammatory conditions of the Central Nervous System is being studied in order to generate novel therapeutic targets.
Carolyn J MacMillan, Carolyn D Doucette, Jordan Warford, Suzanne J Furlong, David W Hoskin, Alexander S Easton   +5 more
doaj   +1 more source