Results 121 to 130 of about 1,147,332 (293)

Angiogenesis in Chronic Obstructive Pulmonary Disease [PDF]

, 2012
Angiogenesis is a crucial component of lung pathophysiology, not only in cancer but also in other disorders, such as chronic obstructive pulmonary disease (COPD).
Gaetano Santulli, Alessandro Matarese
core  

Endogenous angiogenesis inhibitors and their therapeutic implications

, 2001
A number of endogenous inhibitors targeting the tumor vasculature have recently been identified using in vitro and in vivo antiangiogenesis models. While many of these angiogenesis inhibitors display a broad spectrum of biological actions on several ...
Cao, Y,
core   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

random-effects Model of pooled ORR (95% confidence interval) associated with angiogenesis inhibitors in recurrent GBM.

, 2016
random-effects Model of pooled ORR (95% confidence interval) associated with angiogenesis inhibitors in recurrent GBM.
Meng Zhao (54299), Dan Xing (128154), Jie Wang (16762), Yang Yang (45629), Yawei Wang (1445449)   +4 more
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

A Human Bone Defect‐on‐a‐Chip Model for Studying Bone Regeneration

Advanced Materials Technologies, EarlyView.
This study presents a novel human bone defect‐on‐a‐chip (BDOC) model, aiming to recapitulate key processes during early bone healing, incorporating bone graft substitutes. Over 21 days, human mesenchymal stem/stromal cells (HMSCs) and human primary macrophages are co‐cultured in the BDOC together with calcium phosphate microparticles.
Maria Gabriella Fois, Zeinab N. Tahmasebi Birgani, Francesca Giacomini, Alexander P. M. Guttenplan, David Baião Barata, Hoon Suk Rho, Noel Davison, Clemens van Blitterswijk, Martijn van Griensven, Stefan Giselbrecht, Pamela Habibović, Roman K. Truckenmüller   +11 more
wiley   +1 more source

Marine Actinomycetes: A New Source of Angiogenesis Inhibitors

, 2008
As part of our continuous research to develop the biomedical potential of marine organisms, we have focused considerable attention on the marine actinomycetes.
신희재, 이희승, 권호정
core  

Angiogenesis Modulation by Arachidonic Acid-derived Lipids: Positive and Negative Regulators of Angiogenesis

, 2013
Arachidonic acid-derived lipids such as 15 deoxy-PGJ2 or 15 epi-lipoxin A4 have been shown to be potent anti-angiogenesis agents regardless of the angiogenesis stimulus.
Srinivasan, M., Block, R.C., Georas, S., Shaker A. Mousa, Mousa, S.A., Murat Yalcin, Steve Georas, Yalçın, M., Robert C. Block, Mathangi Srinivasan   +9 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Angiogenesis inhibitors for the treatment of epithelial ovarian cancer. [PDF]

Cochrane Database Syst Rev, 2023
Gaitskell K, Rogozińska E, Platt S, Chen Y, Abd El Aziz M, Tattersall A, Morrison J.   +6 more
europepmc   +1 more source