Results 221 to 230 of about 206,338 (257)
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Metalloproteinases and their inhibitors in angiogenesis
Expert Reviews in Molecular Medicine, 2003Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is an integral part of physiological processes such as embryonic development, the female reproductive cycle and wound healing. Angiogenesis is also central to a variety of pathologies including cancer, where it is recognised as being crucial for the growth of solid ...
Lafleur, M.A. +2 more
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Heparin Derivatives as Angiogenesis Inhibitors
Current Pharmaceutical Design, 2003Angiogenesis is the process of generating new capillary blood vessels. Uncontrolled endothelial cell proliferation is observed in tumor neovascularization and in angioproliferative diseases. Tumors cannot growth as a mass above few mm(3) unless a new blood supply is induced. It derives that the control of the neovascularization process may affect tumor
PRESTA, Marco +8 more
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CURCUMIN AS AN INHIBITOR OF ANGIOGENESIS
2007Angiogenesis, the formation of new blood vessels from host vasculature, is critical for tumor growth and metastases. -Curcumin, a novel small-molecular-weight compound, has been shown to inhibit carcinogenesis in different organs and the common link between these actions is its antiangiogenic effect.
Sulochana S, Bhandarkar, Jack L, Arbiser
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Inhibitors of Tumor Angiogenesis
2008Inhibitors of Tumor ...
Harris, Adrian L, GENERALI, DANIELE
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Angiogenesis inhibitors and their delivery systems
Applied Biochemistry and Biotechnology, 1983The extensive vascularity of solid tumors has been recognized for over 100 yr (1). However, only in the past 15 yr has the importance of this phenomenon been appreciated and only in the past 6 yr has the possibility of chemical interference been apparent. In this article, we review the emerging field of tumor vascularization inhibitors.
R, Langer, J, Murray
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Angiogenesis and angiogenesis inhibitors in cancer.
Forum (Genoa, Italy), 1999Angiogenesis, the development of a new blood supply, is an essential process of tumour growth and metastasis. Over the past few years, this has led to the consideration of the tumour vasculature as an optimal target for anti-cancer strategies. The process of angiogenesis consists of a series of interactive events: quiescent endothelial cells are ...
R, Giavazzi, G, Taraboletti
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Update on Endogenous Inhibitors of Angiogenesis
Endothelium, 2006Angiogenesis is regulated by a local balance between the levels of endogenous stimulators and inhibitors of angiogenesis. Understanding of the mechanism of angiogenesis has advanced significantly since the discovery of two members of the family of angiogenesis stimulators, i.e., vascular endothelial growth factor family proteins and angiopoietins ...
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Angiogenesis Inhibitors as Cancer Therapy
Hospital Practice, 1999Angiogenesis inhibitors target a tumor's need to obtain nourishment from the host. In general, they are predicted to be chiefly cytostatic--that is, they stabilize tumors and perhaps prevent metastasis rather than being curative. Nevertheless, it remains conceivable that these agents may trigger tumor cell death.
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[Tumor angiogenesis and tumor angiogenesis inhibitors].
Gan to kagaku ryoho. Cancer & chemotherapy, 2001It is important to survey the molecular targets which are involved in tumor angiogenesis for the development of antiangiogenic agents as one of the cancer therapy. This article is meant to review the recent molecular targets of tumor angiogenesis and the molecular mechanism of antiangiogenic agents in human clinical trials.
M, Ono, M, Kuwano
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Angiogenesis Inhibitors: Current Strategies and Future Prospects
Ca-A Cancer Journal for Clinicians, 2010Kristina M Cook, William D Figg
exaly