Glandular metastases from renal cell carcinoma show poor clinical responses to immune checkpoint inhibition but durable responses to angiogenesis inhibitors. [PDF]
Principe DR+3 more
europepmc +1 more source
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang+12 more
wiley +1 more source
Targeting angiogenesis inhibits tumor infiltration and expression of the pro-invasive protein SPARC
Peter Vajkoczy+11 more
openalex +1 more source
Anginex, a designed peptide that inhibits angiogenesis [PDF]
Arjan W. Griffioen+6 more
openalex +1 more source
Efficacy and safety of angiogenesis inhibitors combined with poly ADP ribose polymerase inhibitors in the maintenance treatment of advanced ovarian cancer: a meta-analysis. [PDF]
Huang R+7 more
europepmc +1 more source
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling [PDF]
ATTOUB, S+11 more
core +1 more source
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
A Novel Snake Venom Disintegrin That Inhibits Human Ovarian Cancer Dissemination and Angiogenesis in an Orthotopic Nude Mouse Model [PDF]
Francis S. Markland+6 more
openalex +1 more source
The emerging issue of cardiac dysfunction induced by antineoplastic angiogenesis inhibitors
C. Tocchetti+9 more
semanticscholar +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source