Results 11 to 20 of about 5,194 (136)

Real-world study and prognostic analysis of angioimmunoblastic T-cell lymphoma [PDF]

Frontiers in Immunology
Jieming Zhang, Qingjiang Chen, Mingzhi Zhang   +2 more
exaly   +2 more sources

The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation

Haematologica, 2010
Background T follicular helper (TFH) cells reside in the light zone of germinal centers and are considered the cell of origin of angioimmunoblastic T-cell lymphoma.
Teresa Marafioti, Jennifer C. Paterson, Erica Ballabio, Andreas Chott, Yasodha Natkunam, Manuel Rodriguez-Justo, Anne Plonquet, Socorro M. Rodriguez-Pinilla, Wolfram Klapper, Martin-L. Hansmann, Stefano A. Pileri, Peter G. Isaacson, Harald Stein, Miguel A. Piris, David Y. Mason, Philippe Gaulard   +15 more
doaj   +1 more source

Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma

Haematologica, 2016
CTLA4 and CD28 are co-regulatory receptors with opposite roles in T-cell signaling. By RNA sequencing, we identified a fusion between the two genes from partial gene duplication in a case of angioimmunoblastic T-cell lymphoma.
Hae Yong Yoo, Pora Kim, Won Seog Kim, Seung Ho Lee, Sangok Kim, So Young Kang, Hye Yoon Jang, Jong-Eun Lee, Jaesang Kim, Seok Jin Kim, Young Hyeh Ko, Sanghyuk Lee   +11 more
doaj   +1 more source

Peripheral T-cell lymphoma: Frequency and distribution in a tertiary referral center in South India

Indian Journal of Pathology and Microbiology, 2012
Background and Aim: Peripheral T/NK-cell lymphomas are uncommon types of non-Hodgkin′s lymphoma (NHL) with a higher frequency in Far East countries as compared to the West.
Deepak K Burad, Manipadam M Therese, Sheila Nair   +2 more
doaj   +1 more source

Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma

Experimental Hematology & Oncology, 2020
Peripheral T-cell lymphomas (PTCLs) are biologically and clinically heterogeneous diseases almost all of which are associated with poor outcomes. Recent advances in gene expression profiling that helps in diagnosis and prognostication of different ...
Caiqin Xie, Xian Li, Hui Zeng, Wenbin Qian   +3 more
doaj   +1 more source

Angioimmunoblastic T-Cell Lymphoma: A Questionable Association with Follicular Dendritic Cell Sarcoma

Case Reports in Hematology, 2017
An elderly woman presented with generalized lymphadenopathy, several systemic symptoms, and splenomegaly. An inguinal lymph node excision revealed a compound picture.
Daniel Benharroch, Miriam Zekzer, Karen Nalbandyan   +2 more
doaj   +1 more source

3D investigation shows walls and wall-like structures around human germinal centres, probably regulating T- and B-cell entry and exit.

PLoS ONE, 2020
This study deals with 3D laser investigation on the border between the human lymph node T-zone and germinal centre. Only a few T-cells specific for antigen selected B-cells are allowed to enter germinal centres.
Miguel Thomos, Patrick Wurzel, Sonja Scharf, Ina Koch, Martin-Leo Hansmann   +4 more
doaj   +1 more source

Two cases of angioimmunoblastic T-cell lymphoma with concomitant positive serology for acute Epstein-Barr virus infection

Hematology Reports, 2017
Angioimmunoblastic T-cell lymphoma (AITL) is a rare type of peripheral T-cell lymphoma. Epstein-Barr virus (EBV) is known to be associated with pathogenesis and histological progression of AITL and the onset of the disease often mimics an infectious ...
Davide Facchinelli, Angela Polino, Francesco Dima, Alice Parisi, Achille Ambrosetti, Dino Veneri   +5 more
doaj   +1 more source

Molecular diagnosis angioimmunoblastic T-cell lymphoma

Терапевтический архив, 2019
Aim: to determine molecular diagnostics routine for different tissue samples in angioimmunoblastic T-cell lymphoma. Materials and methods. Molecular studies were performed for 84 primary AITL patients.
N G Chernova, Y V Sidorova, S Y Smirnova, N V Ryzhikova, E E Nikulina, A M Kovrigina, M N Sinitsyna, A B Sudarikov   +7 more
doaj   +1 more source

PCR-based clonality detection in angioimmunoblastic T-cell lymphoma

Клиническая онкогематология, 2014
In this article, we discuss the issues of angioimmunoblastic T-cell lymphoma diagnosis, particularly the PCR-based methods of clonality detection. Assessments of T-and B-cell clonality was based on TCRG (Vg-Jg), TCRB (Vb-Jb, Db-Jb), IGH (FR1, FR2, and ...
Yu. V. Sidorova, Ye. Ye. Nikulina, N. G. Chernova, L. G. Gorenkova, Ye. A. Gilyazitdinova, S. K. Kravchenko, A. M. Kovrigina, A. B. Sudarikov   +7 more
doaj   +1 more source