Results 41 to 50 of about 5,194 (136)

Granulomatous Vasculitis: An Unusual Manifestation of Metastatic Crohn’s Disease

Australasian Journal of Dermatology, EarlyView.
Ethan Wei Min Lee, Helen Yiling Sun, Christopher W. Toon, Lachlan Andrew Byth   +3 more
wiley   +1 more source

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 9, May 2026.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Angioimmunoblastic T-cell Lymphoma: A Mimic for Lupus

European Journal of Case Reports in Internal Medicine, 2020
New-onset systemic lupus erythematosus (SLE) is uncommon in elderly patients. We report the case of a 71-year-old woman who was diagnosed with SLE based on clinical manifestations of fever, alopecia, bicytopenia, hepatomegaly, lymphadenopathy ...
Hui Boon Tay, Stanley Angkodjojo, Zhi En Amos Tay, Puay Hoon Tan, Yan Denise Tan   +4 more
doaj   +1 more source

Complete hematologic response after belinostat treatment and allogeneic stem cell transplantation for multiple relapsed/refractory angioimmunoblastic T‐cell lymphoma: A case report

Clinical Case Reports, 2023
Key Clinical Message This case report highlights the potential of belinostat for the treatment of relapsed/refractory peripheral T‐cell lymphomas, for which effective therapies are still scarce.
Vincent Camus, Pascaline Etancelin, Fanny Drieux, Elena‐Liana Veresezan, Jean‐Michel Picquenot, Dominique Penther, Mathieu Viennot, Philippe Ruminy, Nathalie Contentin, Emilie Lemasle, Stéphane Leprêtre, Sydney Dubois, Juliette Penichoux, Aspasia Stamatoullas, Alexandra Zduniak, Hélène Lanic, Fabrice Jardin   +16 more
doaj   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration

British Journal of Haematology, Volume 208, Issue 5, Page 1525-1534, May 2026.
Summary Mature T‐cell lymphomas comprise a heterogeneous group of aggressive non‐Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) represents a biologically distinct subtype driven by constitutive activation of ALK fusion ...
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +13 more
wiley   +1 more source

Peripheral Lymphocytosis in Angioimmunoblastic T-cell Lymphoma

International Journal of Advanced Medical and Health Research
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive and unique type of T-cell lymphoma. Patients typically present with constitutional B symptoms, generalized lymphadenopathy, hepatosplenomegaly, cytopenias, and rash.
C. Selvapriya, Nidhya Ganesan, Sakthisankari Shanmugasundaram, Narmadha Rathinasamy, Prasanna Nedungadi Kumar   +4 more
doaj   +1 more source

Incidence of Hodgkin and Non‐Hodgkin Lymphomas: Comparison of the Military and General Population

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Lymphoma risk varies by demographics, environmental/occupational exposures, and medical care between active‐duty service members (ADSM) and the general US population (GUSP). This study compared age‐adjusted incidence rates and trends of Hodgkin lymphoma (HL) and non‐Hodgkin lymphoma (NHL) between these groups.
Kimberly R. Robins, Julie A. Bytnar, Christin B. DeStefano, Craig D. Shriver, Kangmin Zhu   +4 more
wiley   +1 more source

Erdheim‐Chester disease associated with myeloid neoplasm: Clinical features, molecular landscape, and treatment outcomes

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Erdheim‐Chester disease (ECD) is frequently associated with clonal hematopoiesis and myeloid neoplasms (MN), but clinical phenotype and response to kinase inhibitors (KI) in this setting remain unclear. We analyzed 67 patients with ECD associated with MN (ECD‐MN) from a French national cohort and assessed ECD treatment response, MN progression,
Ambroise Le Pogam, Matthias Papo, Pierre Hirsch, Fleur Cohen‐Aubart, Jean‐François Emile, François Delhommeau, Pierre Duffau, Jérôme Razanamahery, Florence Nguyen‐Khac, Christopher Nunes Gomes, Felicien Triboulet, Jeanne de La Rochefoucauld, Chloé McAvoy, Estibaliz Lazaro, Mehdi Hage‐Sleiman, Damien Roos‐Weil, François Chasset, Vincent Jachiet, Arsène Mekinian, Olivier Fain, Zahir Amoura, Jérôme Hadjadj, Julien Haroche   +22 more
wiley   +1 more source

Cutaneous involvement in angioimmunoblastic T-cell lymphoma

Indian Journal of Dermatology, 2010
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive non-Hodgkin′s nodal peripheral T-cell lymphoma characterized by general lymphadenopathy, night sweats, fever, hepatosplenomegaly, polyclonal hypergammaglobulinemia, and cutaneous ...
Papadavid Evangelia, Panayiotides Ioannis, Dalamaga Marianna, Katoulis Alexandros, Economopoulos Theofanis, Stavrianeas Nikolaos   +5 more
doaj