Results 51 to 60 of about 5,194 (136)

Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma

Haematologica, 2007
Background and Objectives In the present paper we report that SAP, an intracytoplasmic molecule that is involved in cell signaling, is an immunohistologic marker for germinal center T cells in paraffin-embedded tissue.
Giovanna Roncador, José-Francisco García Verdes-Montenegro, Sara Tedoldi, Jennifer C. Paterson, Wolfram Klapper, Erica Ballabio, Lorena Maestre, Stefano Pileri, Martin-Leo Hansmann, Miguel A. Piris, David Y. Mason, Teresa Marafioti   +11 more
doaj   +1 more source

Advancing the Diagnosis of Non‐Hodgkin Lymphoma Through Next‐Generation Sequencing in Developing Countries: An Evaluation of Progress—A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Non‐Hodgkin lymphoma (NHL) is the most prevalent hematological malignancy worldwide and accounts for approximately 3% of all cancer cases and fatalities. Next‐generation sequencing (NGS) has advanced molecular diagnosis and targeted treatment in developed countries.
Mohammadreza Saeidnia, Mehdi Shokri, Hassan Nourmohammadi, Safa Radmehr, Mashallah Babashahi, Mohamad Moradi, Maryam Karimian, Mohammad Panji, Elahe Motevaseli   +8 more
wiley   +1 more source

Angioimmunoblastic T-cell Lymphoma: A Case Report

Pakistan Journal of Medicine and Dentistry
Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive type of non-Hodgkin's lymphoma (NHL) that is mostly diagnosed in elderly patients. Its non-specific clinical presentation (lymphadenopathy, fever, night sweats, weight loss, generalized ...
Sundus Nasim, Dua Azim, Farheen Malik, Faryal Tahir, Zehra Ashraf, Abdul Qayyum   +5 more
doaj   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Clonal haematopoiesis in T‐follicular helper cell lymphoma: A prognostic biomarker and early event in lymphoma evolution

British Journal of Haematology, Volume 208, Issue 4, Page 1223-1231, April 2026.
Summary T‐follicular helper cell lymphomas (TFHLs) are frequently associated with epigenetic mutations and clonal haematopoiesis (CH), but the clinical and prognostic implications of CH in TFHL remains unclear. We performed next‐generation sequencing on paired peripheral blood (PB) and tumour tissue samples from 30 patients with TFHL. CH was defined by
Chong Wei, Yan Zhang, Danqing Zhao, Wei Zhang, Daobin Zhou   +4 more
wiley   +1 more source

Primary nodal peripheral T-cell lymphomas: diagnosis and therapeutic considerations

Revista Brasileira de Hematologia e Hemoterapia, 2015
Nodal peripheral T-cell lymphomas are a rare group of neoplasms derived from post-thymic and activated T lymphocytes. A review of scientific articles listed in PubMed, Lilacs, and the Cochrane Library databases was performed using the term "peripheral T ...
Luis Alberto de Pádua Covas Lage, Tamara Carvalho dos Santos Cabral, Renata de Oliveira Costa, Marianne de Castro Gonçalves, Debora Levy, Maria Cláudia Nogueira Zerbini, Juliana Pereira   +6 more
doaj   +1 more source

Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine

Frontiers in Oncology, 2020
Peripheral T-cell lymphoma (PTCL) is a rare, heterogenous group of mature T-cell neoplasms that comprise 10–15% of non-Hodgkin lymphoma cases in the United States. All subtypes of PTCL, except for ALK+ anaplastic T-cell lymphoma, are associated with poor
Yumeng Zhang, Dasom Lee, Thomas Brimer, Mohammad Hussaini, Lubomir Sokol   +4 more
doaj   +1 more source

Complete hematologic response in a patient with multiple pretreated angioimmunoblastic T‐cell lymphoma after belinostat therapy followed by allogeneic stem cell transplantation: A case report

Clinical Case Reports
Key Clinical Message Belinostat therapy followed by hematopoietic stem cell transplantation is a promising salvage strategy for heavily pretreated patients with peripheral T‐cell lymphoma.
Sigrid De Wilde, Carlos Graux
doaj   +1 more source

A Case of Angioimmunoblastic T-Cell Lymphoma

Journal of Clinical and Diagnostic Research
Angioimmunoblastic T-cell Lymphoma (AITL) is a rare type of peripheral T-cell lymphoma characterised by an aggressive clinical course and a poor response to current therapies. There is currently no standard of care for treatment.
Kanchan Dasharthrao Devde, Amol Gajanan Andhale, Amol Shankar Dongre, Himanshi Kaushik, Prerna Tekulware   +4 more
doaj   +1 more source

Delayed diagnosis of angioimmunoblast T-cell lymphoma presenting with immunoglobulin a vasculitis

Renal Failure
Although vasculitis and renal involvement might be associated with malignancy, they are rarely associated with lymphoproliferative diseases. We observed a case of immunoglobulin A vasculitis associated with segmental and focal glomerulonephritis in a ...
Lu Xu, Huihui Dong, Dandan Xue, Yiming Zhang, Xinjian Li   +4 more
doaj   +1 more source