Results 11 to 20 of about 5,168 (136)

Sustained Belinostat‐Induced Metabolic Response and Tolerability in Heavily Pretreated Relapsed/Refractory Angioimmunoblastic T‐Cell Lymphoma: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Angioimmunoblastic T‐cell lymphoma (AITL), a rare and aggressive subtype of peripheral T‐cell lymphoma (PTCL), often demonstrates resistance to standard therapies. The optimal therapeutic approach for relapsed/refractory (R/R) AITL remains therefore uncertain and challenging, with an unmet need for effective treatment options.
Vassiliki Labropoulou, Evgenia Verigou, Eleni P. Kourea, Maria Liga, Dimitrios Tsokanas, Krisela‐Christina Valera, Alexandros Spyridonidis   +6 more
wiley   +2 more sources

In vivo CAR T cell therapy against angioimmunoblastic T cell lymphoma. [PDF]

J Exp Clin Cancer Res
Background For angioimmunoblastic T cell lymphoma (AITL), a rare cancer, no specific treatments are available and survival outcome is poor. We previously developed a murine model for AITL that mimics closely human disease and allows to evaluate new ...
Krug A, Saidane A, Martinello C, Fusil F, Michels A, Buchholz CJ, Ricci JE, Verhoeyen E.   +7 more
europepmc   +2 more sources

Peripheral T-Cell Lymphomas of the T Follicular Helper Type: Clinical, Pathological, and Genetic Attributes

Hemato, 2022
Follicular helper T-cell (TFH) lymphomas comprise a unique group of T-cell lymphomas that represent neoplastic proliferations of follicular helper T-cells and share genetic, immunophenotypic, morphologic, and clinical features.
Karthik A. Ganapathi, Kristin H. Karner, Madhu P. Menon   +2 more
doaj   +1 more source

Spontaneous remission of angioimmunoblastic T-cell lymphoma in a child with ataxia–telangiectasia: a case report

Journal of Medical Case Reports, 2023
Background Angioimmunoblastic T-cell lymphoma is an uncommon subtype of peripheral T-cell lymphoma in children with fewer than 20 cases reported in literature.
Dima Abla, Abeer Al-Battashi, Khalil Albiroty, Khuloud Abu Qasida, Nasser Al-Rahbi, Salah Al-Awaidy   +5 more
doaj   +1 more source

A phase I dose-escalation study of neoantigen-activated haploidentical T cell therapy for the treatment of relapsed or refractory peripheral T-cell lymphoma

Frontiers in Oncology, 2022
Peripheral T-cell lymphoma (PTCL) is a type of highly heterogeneous non-Hodgkin lymphoma with a poor prognosis and lack of effective targeted therapies. Adoptive T-cell therapy has been successfully used in the treatment of B-cell malignancies.
Yuan Chen, Hu Zhao, Jing Luo, Youping Liao, Xu Dan, Guoyu Hu, Weiyue Gu   +6 more
doaj   +1 more source

Prolonged chemotherapy for angioimmunoblastic T-cell lymphoma

Клиническая онкогематология, 2014
Introduction: Current СНОР-like therapy for angioimmunoblastic T-cell lymphoma demonstrates unsatisfactory results with respect to the achievement of complete remission.
N. G. Chernova, Yu. E. Vinogradova, Yu. V. Sidorova, I. B. Kaplanskaya, E. A. Gilyazitdinova, L. G. Gorenkova, D. S. Marin, A. M. Kremenetskaya, A. I. Vorobyev, S. K. Kravchenko   +9 more
doaj   +1 more source

Chemotherapy combined with radiotherapy for successful treatment of angioimmunoblastic T-cell lymphoma: a case report

Journal of Medical Case Reports, 2020
Background The incidence of angioimmunoblastic T-cell lymphoma is rare worldwide, and it has a poor prognosis. There is no proven or standard first-line therapy that works for the majority of patients with angioimmunoblastic T-cell lymphoma because of ...
Yudi Xiong, Lei Yang, Jing Dai, Fuxiang Zhou, Yunfeng Zhou   +4 more
doaj   +1 more source

Epstein–Barr virus positive diffuse large B‐cell lymphoma transformed into angioimmunoblastic T‐cell lymphoma after treatment

Clinical Case Reports, 2021
Angioimmunoblastic T‐cell lymphoma (AITL) is the subtype of mature T‐cell non‐Hodgkin lymphoma. Compared with diffuse large B‐cell lymphoma (DLBCL), AITL patients are frequently accompanied with Epstein–Barr virus (EBV) infection.
Chaoyu Wang, Yi Gong, Qingming Jiang, Xiping Liang, Rui Chen   +4 more
doaj   +1 more source

Angioimmunoblastic T-cell lymphoma presenting as giant kidneys: a case report

Journal of Medical Case Reports, 2009
Introduction Angioimmunoblastic T-cell lymphoma is a rare form of tumor of the lymph nodes or lymphoid tissue. In this report we describe an unusual presentation of angioimmunoblastic T-cell lymphoma consisting of giant kidneys with no nephrotic syndrome.
Argov Ori, Charach Gideon, Weintraub Moshe, Shtabsky Alexander   +3 more
doaj   +1 more source

Renal infarction due to polyarteritis nodosa in a patient with angioimmunoblastic T-cell lymphoma: a case report and a brief review of the literature

Diagnostic Pathology, 2012
Angioimmunoblastic T-cell lymphoma is one of the most common subtypes of peripheral T-cell lymphoma (15-20% of all cases), accounting for approximately 1-2% of all non-Hodgkin lymphomas.
Ambrosio Maria, Rocca Bruno, Ginori Alessandro, Onorati Monica, Fabbri Alberto, Carmellini Mario, Lazzi Stefano, Tripodi Sergio   +7 more
doaj   +1 more source