Results 31 to 40 of about 14,294,829 (187)

Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma

Haematologica, 2016
CTLA4 and CD28 are co-regulatory receptors with opposite roles in T-cell signaling. By RNA sequencing, we identified a fusion between the two genes from partial gene duplication in a case of angioimmunoblastic T-cell lymphoma.
Hae Yong Yoo, Pora Kim, Won Seog Kim, Seung Ho Lee, Sangok Kim, So Young Kang, Hye Yoon Jang, Jong-Eun Lee, Jaesang Kim, Seok Jin Kim, Young Hyeh Ko, Sanghyuk Lee   +11 more
doaj   +1 more source

Advances in understanding of angioimmunoblastic T-cell lymphoma [PDF]

Leukemia, 2020
AbstractIt has been nearly half a century since angioimmunoblastic T-cell lymphoma (AITL) was characterized in the early 1970’s. Our understanding of the disease has dramatically changed due to multiple discoveries and insights. One of the key features of AITL is aberrant immune activity.
Shigeru Chiba, Mamiko Sakata-Yanagimoto
openaire   +2 more sources

Peripheral T-cell lymphoma: Frequency and distribution in a tertiary referral center in South India

Indian Journal of Pathology and Microbiology, 2012
Background and Aim: Peripheral T/NK-cell lymphomas are uncommon types of non-Hodgkin′s lymphoma (NHL) with a higher frequency in Far East countries as compared to the West.
Deepak K Burad, Manipadam M Therese, Sheila Nair   +2 more
doaj   +1 more source

Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma

Experimental Hematology & Oncology, 2020
Peripheral T-cell lymphomas (PTCLs) are biologically and clinically heterogeneous diseases almost all of which are associated with poor outcomes. Recent advances in gene expression profiling that helps in diagnosis and prognostication of different ...
Caiqin Xie, Xian Li, Hui Zeng, Wenbin Qian   +3 more
doaj   +1 more source

Real-world study and prognostic analysis of angioimmunoblastic T-cell lymphoma [PDF]

Frontiers in Immunology
Qingjiang Chen, Mingzhi Zhang, Jieming Zhang   +2 more
exaly   +2 more sources

B-cell lymphoma showing typical features of angioimmunoblastic T-cell lymphoma [PDF]

, 2008
We present a 52-year-old man who was diagnosed with B cell-derived angioimmunoblastic lymphoma. He was admitted with systemic, including mediastinal and para-aortic, lymphadenopathy, fever and skin itching.
Ozawa, Keiya, Mori, Masaki, Muroi, Kazuo, Nagai , Tadashi, Furukawa , Yusuke, Takatoku, Masaaki   +5 more
core   +1 more source

3D investigation shows walls and wall-like structures around human germinal centres, probably regulating T- and B-cell entry and exit.

PLoS ONE, 2020
This study deals with 3D laser investigation on the border between the human lymph node T-zone and germinal centre. Only a few T-cells specific for antigen selected B-cells are allowed to enter germinal centres.
Miguel Thomos, Patrick Wurzel, Sonja Scharf, Ina Koch, Martin-Leo Hansmann   +4 more
doaj   +1 more source

Regulatory T-Cell Depletion in Angioimmunoblastic T-Cell Lymphoma [PDF]

The American Journal of Pathology, 2010
Angioimmunoblastic T-cell lymphoma (AITL) is the most frequent nodal T-cell lymphoma and is characterized by a polymorphic lymph node infiltrate, various dysimmune disorders, and a poor prognosis. Regulatory T-cells (Treg) play an emerging role in the prognosis of non-Hodgkin B-cell lymphoma and mediate significant autoreactive T-cell suppression.
Bruneau, Julien, Canioni, D., Renand, A., Marafioti, T., Paterson, J.C., Martin-Garcia, N., Gaulard, P., Delfau, M.H., Hermine, O., Macintyre, E., Brousse, N., Asnafi, V.   +11 more
openaire   +3 more sources

Two cases of angioimmunoblastic T-cell lymphoma with concomitant positive serology for acute Epstein-Barr virus infection

Hematology Reports, 2017
Angioimmunoblastic T-cell lymphoma (AITL) is a rare type of peripheral T-cell lymphoma. Epstein-Barr virus (EBV) is known to be associated with pathogenesis and histological progression of AITL and the onset of the disease often mimics an infectious ...
Davide Facchinelli, Angela Polino, Francesco Dima, Alice Parisi, Achille Ambrosetti, Dino Veneri   +5 more
doaj   +1 more source

Angioimmunoblastic T-cell lymphoma: the many-faced lymphoma [PDF]

Blood, 2017
AbstractAngioimmunoblastic T-cell lymphoma (AITL) is an uncommon subtype of mature peripheral T-cell lymphoma (PTCL). The history of AITL is much longer and deeper than the literature would suggest given the many names that have preceded it. Advanced-stage disease is common with uncharacteristic laboratory and autoimmune findings that often slow or ...
Matthew A, Lunning, Julie M, Vose
openaire   +2 more sources