Results 141 to 150 of about 20,336,744 (217)

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

The effect of hypoxia and the hypoxia mimetic agent L-mimosine on the production of angiopoietin-like 4 in fibroblasts of the gingiva and the periodontal ligament

, 2017
Einleitung: In der Zahnheilkunde stellt die Entwicklung von parodontalen Erkrankungen ein akutes Problem dar. Um unsere Kenntnisse über die Ätiologie und Therapie parodontaler Erkrankungen zu erweitern, ist ein umfassenderes Verständnis der Auswirkungen ...
Schellner, Alwina
core  

Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis, Davi Araújo, Asaf Wilensky, Juliana Girón Bastidas, Stella Alimperti, Flavia Pirih   +5 more
wiley   +1 more source

Der Effekt von Hypoxie und dem Hypoxie-Mimetikum L-Mimosin auf die Produktion von Angiopoietin-like 4 in Fibroblasten der Gingiva und des parodontalen Ligaments

, 2017
Einleitung: In der Zahnheilkunde stellt die Entwicklung von parodontalen Erkrankungen ein akutes Problem dar. Um unsere Kenntnisse über die Ätiologie und Therapie parodontaler Erkrankungen zu erweitern, ist ein umfassenderes Verständnis der Auswirkungen ...
Schellner, Alwina
core  

Angiopoietin-like 4 : a decade of research

, 2012
The past decade has seen a rapid development and increasing recognition of ANGPTL4 (angiopoietin-like 4) as a remarkably multifaceted protein that is involved in many metabolic and non-metabolic conditions. ANGPTL4 has been recognised as a central player
Goh, Yan Yih, Tan, Nguan Soon, Chin, Alison Hwee Fang, Zhu, Pengcheng, Kersten, Sander   +4 more
core   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Does angiopoietin-like protein 4 (ANGPTL4) plays a role in apoptosis?

, 2008
Anoikis is apoptosis induced by the loss of cell adhesion, which is involved in tissue homeostatsis, wound repair and cancer metastasis. It has been shown that the expression of Fasting Induced Adipose Factor (FIAF), also known as angiopoietin-like ...
Lin, Jiayi
core  

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease

, 2018
Introduction: The aim of the current study was to examine the difference between patients detected with nonalcoholic fatty liver disease (NAFLD) and healthy subjects in terms of serum angiopoietin-like protein (ANGPTL) 2 and ANGPTL6 levels and to ...
Erkan, Gulbanu and Muratoglu, Suzan and Ercin, Ugur and Bilgihan, Ayse
core   +1 more source

Fisetin Attenuates Human Macrophage Polarization and Pro‐Inflammatory Responses via NLRP3 and NF‐κB/MAPK Suppression

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Natural compounds with anti‐inflammatory properties are increasingly explored as therapeutic agents due to their lower risk of side effects compared with conventional drugs. Fisetin, a dietary bioflavonol abundant in fruits and vegetables, exhibits anti‐inflammatory activity in several cell types, including murine macrophages.
Nattaya Onpan, Chanchao Lorthongpanich, Pakpoom Kheolamai, Pimjai Chingsuwanrote, Napachai Rodboon, Sudjit Luanpitpong, Chonticha Saisawang, Surapol Issaragrisil   +7 more
wiley   +1 more source