Results 61 to 70 of about 891,437 (121)

Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice[S]

Journal of Lipid Research, 2019
Angiopoietin-like protein (ANGPTL)4 regulates plasma lipids, making it an attractive target for correcting dyslipidemia. However, ANGPTL4 inactivation in mice fed a high fat diet causes chylous ascites, an acute-phase response, and mesenteric ...
Antwi-Boasiako Oteng, PhilipM.M. Ruppert, Lily Boutens, Wieneke Dijk, XantheA.M.H. van Dierendonck, Gunilla Olivecrona, Rinke Stienstra, Sander Kersten   +7 more
doaj   +1 more source

Regulatory and functional mechanism of angiopoietin-like protein-4 in gastric epithelial cells with Helicobacter pylori infection

陆军军医大学学报
Objective To explore the regulatory and functional mechanism of angiopoietin-like 4 (ANGPTL4) expression in gastric epithelial cells infected with Helicobacter pylori (H.pylori).
CHEN Wanyan, YUE Gengyu, XU Xiaolin
doaj   +1 more source

Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer

Cancer Communications
Background Lymph node metastasis (LNM) is the primary mode of metastasis in gastric cancer (GC). However, the precise mechanisms underlying this process remain elusive.
Jian Xiao, Shuqing Cao, Jiawei Wang, Pengyu Li, Quan Cheng, Xinyi Zhou, Jiacheng Dong, Yuan Li, Xinyu Zhao, Zekuan Xu, Li Yang   +10 more
doaj   +1 more source

Differential regulation and properties of angiopoietin-like proteins 3 and 4

Journal of Lipid Research, 2005
Angiopoietin-like protein 3 and 4 (Angptl3 and Angptl4) are two members of the angiopoietin-like family of proteins. These two closely related proteins have been reported to similarly affect lipid metabolism through their capacity to inhibit lipoprotein ...
Hongfei Ge, Ji-Young Cha, Harini Gopal, Christopher Harp, Xinxin Yu, Joyce J. Repa, Cai Li   +6 more
doaj   +1 more source

Serum angiopoietin-like 4 protein levels and expression in adipose tissue are inversely correlated with obesity in monozygotic twins

Journal of Lipid Research, 2011
Animal studies have suggested that angiopoietin-like 4 (Angptl4) regulates adiposity through central and peripheral mechanisms. The aim of this study was to investigate whether serum concentration and adipose tissue expression of Angptl4 are associated ...
Marius R. Robciuc, Jussi Naukkarinen, Alfredo Ortega-Alonso, Henna Tyynismaa, Taneli Raivio, Aila Rissanen, Jaakko Kaprio, Christian Ehnholm, Matti Jauhiainen, Kirsi H. Pietiläinen   +9 more
doaj   +1 more source

The role of Vitamin D in malaria

Journal of Infection in Developing Countries, 2015
An abnormal calcium-parathyroid hormone (PTH)-vitamin D axis has been reported in patients with malaria infection. A role for vitamin D in malaria has been suggested by many studies. Genetic studies have identified numerous factors that link vitamin D to
Khanh Vinh Quốc Luong, Lan Thi Hoàng Nguyen   +1 more
doaj   +1 more source

The serum ANGPTL4 level and severe coronary artery calcification: from association to risk prediction using a nomogram

Frontiers in Cardiovascular Medicine
BackgroundCoronary artery calcification (CAC) is an important indicator of atherosclerosis in the coronary arteries, the degree of which is closely associated with the risk for cardiovascular events.
Yan Sun, Mengchen Li, Dai Zhang, Yujing Cheng, Yu Liu, Jialong Niu, Hailong Ge, Xiaoli Liu, Hongya Han   +8 more
doaj   +1 more source

Corrigendum to "Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4" [Genes & Diseases 9(2022) 443-455]. [PDF]

Genes Dis, 2022
Shen X, Weng C, Wang Y, Wang C, Feng S, Li X, Li H, Jiang H, Wang H, Chen J.   +9 more
europepmc   +1 more source

The serum levels of angiopoietin‐like protein 3 and 4 in type 2 diabetic patients with and without metabolic syndrome compared to the control group

Endocrinology, Diabetes & Metabolism
Introduction ANGPTLs (Angiopoietin‐like proteins) 3 and 4 play an important role in the development of type 2 diabetes. These glycoproteins affect the modulation of glucose and lipid metabolism.
Sharabeh Hezarkhani, Aytekin Hajighaderi, Sara Hosseinzadeh, Naser Behnampour, Gholamreza Veghari, Farshid Fathabadi, Zahra Hesari, Hamid Reza Joshaghani   +7 more
doaj   +1 more source

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS

BMC Medicine
Background Alterations in lipid metabolism are manifestations of amyotrophic lateral sclerosis (ALS) that contribute to the risk and rate of progression.
Sruthi Sankari Krishnamurthy, Adriana Zardini Buzatto, Caley Campkin, Hans-Peter Müller, Diana Wiesner, Jochen Weishaupt, Veronika Klose, Maximilian Wiesenfarth, Zeynep Elmas, Christine Herrmann, Özlem Parlak, Kornelia Günther, Rami Saad, Ulrike Weiland, Luc Dupuis, Albert Ludolph, Liang Li, Jan Kassubek, Johannes Dorst, Francesco Roselli   +19 more
doaj   +1 more source