Results 231 to 240 of about 97,423,779 (276)

The clinical value of angiopoietin‐2 in liver diseases

Clinical Liver Disease, 2022
Content available: Audio Recording.
Maham, Farshidpour, Spencer, Pace, Michael L, Volk   +2 more
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Flow‐dependent regulation of angiopoietin‐2

Journal of Cellular Physiology, 2007
AbstractEndothelial cells are constantly exposed to high or low shear stress in arteries and veins by the flowing blood. Angiopoietin‐2 (Ang‐2) is acting as a critical regulator of vessel maturation and endothelial cell quiescence. In this study, flow‐dependent regulation of Ang‐2 was analyzed in vitro and in vivo.
Winfried, Goettsch, Corina, Gryczka, Thomas, Korff, Evelyn, Ernst, Claudia, Goettsch, Jochen, Seebach, Hans-Joachim, Schnittler, Hellmut G, Augustin, Henning, Morawietz   +8 more
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Angiopoietin-2 in CLL

Blood, 2010
Elevated plasma levels of the angiogenic factor Ang-2 correlated with poor prognosis in a larger series of CLL patients. Ang-2 levels may reflect crosstalk between CLL cells and their microenvironment, specifically related to angiogenesis and endothelial cells, and therefore emphasize the importance of angiogenesis in CLL. .
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Angiopoietin-2 in acute liver failure*

Critical Care Medicine, 2012
Angiopoietin-2, an antagonistic ligand of the endothelial Tie2 receptor, has been identified as a gatekeeper of endothelial activation. We examined whether the release of Angiopoietin-2 correlates with surrogates of organ dysfunction and outcome in patients with acute liver failure.Retrospective clinical and immunohistological study.Intensive care unit
Johannes, Hadem, Clemens L, Bockmeyer, Alexander, Lukasz, Sven, Pischke, Andrea S, Schneider, Heiner, Wedemeyer, Danny, Jonigk, Michael P, Manns, Philipp, Kümpers   +8 more
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Angiopoietin-2 in der Intensivmedizin

Intensivmedizin und Notfallmedizin, 2009
Das Endothel ist eine wichtige Schnittstelle zwischen Immun-, Gerinnungs- und Komplementsystem. Im Rahmen von SIRS und Sepsis kommt es zu einer Aktivierung von Endothelzellen, die daraufhin aus einem relativen Ruhezustand in einen proinflammatorischen, prokoagulatorischen und proadhasiven Status wechseln.
P. Kümpers, S. David
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Circulating angiopoietin-2 levels in the course of septic shock: relation with fluid balance, pulmonary dysfunction and mortality [PDF]

Intensive Care Medicine, 2009
Contains fulltext : 79899.pdf (Publisher’s version ) (Open Access)PURPOSE: To investigate whether angiopoietin-2, von Willebrand factor (VWF) and angiopoietin-1 relate to surrogate indicators of vascular permeability, pulmonary ...
Peter Pickkers, Geerten P van Nieuw Amerongen   +1 more
exaly   +2 more sources

Expression of heparanase and angiopoietin-2 in patients with endometriosis

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2008
The objective was to investigate the expression of heparanase (Hpa) and angiopoietin-2 (Ang-2) in endometriosis.In ectopic and eutopic endometrium of patients undergoing laparoscopy for endometriosis (n=86) and in normal endometrium of patients undergoing laparoscopic tubal ligation or hysteroscopic resection because of uterus septus (n=30), we ...
Cai, Jingting, Zhang, Yangde, Zhang, Yi, Li, Mengxiong, Yu, Rong, Zhang, Yu, Peng, Guoqing, Peng, Lixiu   +7 more
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Expression and regulation of murine macrophage angiopoietin-2

Cellular Immunology, 2005
Our understanding of angiogenesis has increased significantly in the past few years with the discovery of angiopoietins (Ang). Specifically, Ang2 has been associated with pathologic as well as normal vascularization. While previous studies have shown that a major source of Ang2 has been endothelial cells and tumor cells, we reasoned that macrophages ...
Neil E, Hubbard, Debora, Lim, Mithia, Mukutmoni, Ann, Cai, Kent L, Erickson   +4 more
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Targeting angiopoietin-2 signaling in cancer therapy

Expert Opinion on Investigational Drugs, 2013
Over the past decade, several anti-angiogenic strategies have been devised to target a wide spectrum of malignancies. The most widely utilized approach involves abrogation of vascular endothelial growth factor receptor signaling through either consumption of ligand (i.e., with the monoclonal antibody bevacizumab) or through direct inhibition of the ...
Zeynep, Eroglu, Cy A, Stein, Sumanta K, Pal   +2 more
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[Correlation of angiopoietin-2 and angiopoietin-2 receptor expressions in serum and placenta with preeclampsia].

Zhonghua fu chan ke za zhi, 2012
To investigate the correlation of the expressions of angiopoietin-2 (Ang-2) and angiopoietin-2 receptor (Tie-2) in serum and placenta with preeclampsia.From May 2009 to April 2010, 62 women with preeclampsia who delivered in Affiliated Hospital of Qingdao University Medical College were recruited in the study, including 30 women with moderate ...
Li-jing, Wang, Wei-ping, Chen, Wei, Peng, Lin, Xu, Ai-hua, Sui, Yuan-hua, Ye   +5 more
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