Results 121 to 130 of about 75,908 (219)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

The effect of hypoxia and the hypoxia mimetic agent L-mimosine on the production of angiopoietin-like 4 in fibroblasts of the gingiva and the periodontal ligament

, 2017
Einleitung: In der Zahnheilkunde stellt die Entwicklung von parodontalen Erkrankungen ein akutes Problem dar. Um unsere Kenntnisse über die Ätiologie und Therapie parodontaler Erkrankungen zu erweitern, ist ein umfassenderes Verständnis der Auswirkungen ...
Schellner, Alwina
core  

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Der Effekt von Hypoxie und dem Hypoxie-Mimetikum L-Mimosin auf die Produktion von Angiopoietin-like 4 in Fibroblasten der Gingiva und des parodontalen Ligaments

, 2017
Einleitung: In der Zahnheilkunde stellt die Entwicklung von parodontalen Erkrankungen ein akutes Problem dar. Um unsere Kenntnisse über die Ätiologie und Therapie parodontaler Erkrankungen zu erweitern, ist ein umfassenderes Verständnis der Auswirkungen ...
Schellner, Alwina
core  

Angiopoietin-like-4 is a potential angiogenic mediator in arthritis

, 2005
Our previous studies of gene expression profiling during collagen-induced arthritis (CIA) indicated that the putative angiogenic factor Angptl4 was one of the most highly expressed mRNAs early in disease.
Witte, D.P., Sowders, D., Grom, A., Kersten, A.H., Hermann, L.M., Jennings, K., Yang, L., Pinkerton, M., Hirsch, R., Thornton, S.   +9 more
core   +1 more source

Angiopoietin-like protein 4 treated bone marrow-derived mesenchymal stem cells alleviate myocardial injury of patients with myocardial infarction. [PDF]

Nurs Health Sci, 2022
Zhang F, Wu J, Li X, Ying X, Fang W, Dong Y.   +5 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

The serum ANGPTL4 level and severe coronary artery calcification: from association to risk prediction using a nomogram

Frontiers in Cardiovascular Medicine
BackgroundCoronary artery calcification (CAC) is an important indicator of atherosclerosis in the coronary arteries, the degree of which is closely associated with the risk for cardiovascular events.
Yan Sun, Mengchen Li, Dai Zhang, Yujing Cheng, Yu Liu, Jialong Niu, Hailong Ge, Xiaoli Liu, Hongya Han   +8 more
doaj   +1 more source

Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway. [PDF]

Oxid Med Cell Longev, 2022
Jia C, Li X, Pan J, Ma H, Wu D, Lu H, Wang W, Zhang X, Yi X.   +8 more
europepmc   +1 more source

Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 74-88, July 2026.
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani, Katharina Remih, Anna Sophie Karl, Julia Alexandra Borchert, Christina Schrader, Malin Fromme, Can Kayatekin, Bailin Zhang, Mikhail Levit, Pavithra Krishnaswami, Louise E. van Eekeren, Leo A. B. Joosten, Twan Otten, Petra Tomanová, Pavel Strnad   +14 more
wiley   +1 more source