Results 151 to 160 of about 75,908 (219)

Human brain pericytes protect the blood–brain barrier from triple‐negative breast cancer cells while promoting tumor aggressiveness

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract The majority of breast cancer‐related deaths result from metastatic progression, especially brain metastasis, associated with the poorest prognosis. Patients with triple‐negative breast cancer (TNBC) are particularly prone to developing brain metastases.
Eloise Happernegg, Marine Carroué, Julien Cicero, Lucie Dehouck, Fumitaka Shimizu, Takashi Kanda, Chann Lagadec, Fabien Gosselet, Xuefen Le Bourhis, Maxime Culot, Robert‐Alain Toillon, Caroline Mysiorek   +11 more
wiley   +1 more source

Molecular and biochemical characterization of subtilisin-like proteases in arabidopsis thaliana [PDF]

, 2000
Subtilisin-like proteases form a large group of serine proteases with diverse functions, including the specific processing of a variety of proproteins and prohormones, and are found in prokaryotic and eukaryotic organisms. The work in this thesis focuses
Hamilton, John Michael Uwe
core  

Extracellular Vesicles as Drivers of Lung Endothelial Dysfunction in ARDS: Mechanisms and Therapeutic Opportunities

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni, Patrick Belvitch, Steven M. Dudek, Eleftheria Letsiou   +3 more
wiley   +1 more source

Investigation of human angptl4 (angiopoietin-like 4) levels in patients diagnosed with pulmonary thromboembolism

Pulmoner tromboemboli tanısı ve klinik olarak şüphelenilmesi zor hastalıklardan biridir. Skorlamaların ve tanıda kullanılan parametrelerin yetersizliği nedeniyle halen pulmoner tromboemboli atlanabilen ve mortal seyreden hastalık tablolarından biridir ...
Çolak, Elif Burcu Pektaş
core  

Corrigendum to "Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4" [Genes Dis DOI: 10.1016/j.gendis.2020.07.005]. [PDF]

Genes Dis, 2022
Shen X, Weng C, Wang Y, Wang C, Feng S, Li X, Li H, Jiang H, Wang H, Chen J.   +9 more
europepmc   +1 more source

シシツ イジョウ ドウミャク コウカ オヨビ マクロファージ ホウマツカ ケイセイ ニ カンスル Angiopoetin like protein family 4 Angptl4 ノ ヤクワリ

, 2009
In 2000，several groups repoted Angiopoetin like protein family 4 (Angptl 4) as one of "angiopoietin-like proteins" (Angptls). Angptls possess an N-terminal coiled-coil domain and a C-terminal, both characteristic of angiopoietins. However, Angptls de not
足立, 博紀, アダチ, ヒロノリ, Adachi, Hironori   +2 more
core  

The binding and activation of the glucagon-like peptide-1 receptor by exendin-4 [PDF]

, 2010
Background and purpose Exendin-4 (EX4) has the same physiological properties as glucagon-like peptide-1 (7-36)amide (GLP-1). EX4 has 50% identity with GLP-1, with an extra nine amino acids at its C-terminus.
Nasr, Elsayed Mohammed Nasr
core  

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, Volume 10, Issue 3, Page 269-280, June 2026.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li, Simone Staffer, Sabine Tuma‐Kellner, Uta Merle, Walee Chamulitrat   +4 more
wiley   +1 more source