Results 61 to 70 of about 4,326 (177)

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway

PPAR Research, 2017
The angiopoietin-like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins structurally related to factors modulating angiogenesis known as angiopoietins.
Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale   +6 more
doaj   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, EarlyView.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, Volume 59, Issue 7, Page 1402-1415, July 2026.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease

, 2010
Objective—To investigate the relationship between angiopoietin-like protein 4 (Angptl4) levels, coronary heart disease (CHD) biomarkers, and ANGPTL4 variants.
Braund, Peter S., Kumari, Meena, Hall, Alistair S., Samani, Nilesh J., Smart-Halajko, Melissa C., Kay-tee Khaw, Steve E. Humphries, Mika Kivimaki, Nilesh J. Samani, Kivimaki, Mika, Boekholdt, S. Matthijs, Marius R. Robciuc, Christopher P. Nelson, Alistair S. Hall, Nelson, Christopher P., Jackie A. Cooper, Meena Kumari, Melissa C. Smart-halajko, Khaw, Kay-Tee, Nicholas J. Wareham, Tom R. Gaunt, Gaunt, Tom R., Khaw, Kay Tee, Peter S. Braund, Ehnholm, Christian, S. Matthijs Boekholdt, Wareham, Nicholas J., Philippa J. Talmud, Jauhiainen, Matti, Matti Jauhiainen, Day, Ian N., Robciuc, Marius R., Talmud, Philippa J., Humphries, Steve E., Cooper, Jackie A., Christian Ehnholm, Ian N. Day   +36 more
core   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, Volume 13, Issue 30, 28 May 2026.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Development

, 2013
Item does not contain fulltextOBJECTIVE: Macrophage foam cells play a crucial role in several pathologies including multiple sclerosis, glomerulosclerosis, and atherosclerosis.
Vliet, A., van der, Tan, Nguan Soon, Stalenhoef, Anton, Stienstra, R., de Roos, Albert, Stalenhoef, A.F., Janssen, Aafke, Smit, J.W.A., Müller, M.R., van der Vliet, J Adam, Roos, J.A., de, Tjeerdema, N., Kersten, S., Stienstra, Rinke, Roos, A. de, Wang, Y.A., Kersten, Sander, Tan, N.S., van der Vliet, A., Vliet, J.A. van der, Kersten, A.H., Tjeerdema, Nathanja, Georgiadi, Anastasia, Müller, Michael, Janssen, A., Georgiadi, A., Muller, M, Rensen, P.C.N., Smit, Johannes W A, Smit, J.W., Rensen, P.C., Wang, Yanan, Stalenhoef, A., de Roos, J.A., Tamsma, J.T., Tamsma, Jouke T, Müller, M., Wang, Y., Rensen, Patrick C N   +38 more
core   +1 more source

Angiopoietin-like4 can be used to evaluate and predict efficacy for membranous nephropathy

Linchuang shenzangbing zazhi, 2019
Objective To investigate the feasibility of serum and urine angiopoietin-like 4(Angptl4) for evaluating and predicting efficacy for membranous nephropathy.
WANG Jian, NING Li, WANG Run-xiu, CAO Feng   +3 more
doaj  

Hepatitis C Virus and Type 2 Diabetes: Mechanisms, Clinical Impact, and Post‐DAA Management

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Hepatitis C virus (HCV) infection remains a major global health burden despite advances in direct‐acting antiviral (DAA) therapies. Beyond hepatic complications such as cirrhosis and hepatocellular carcinoma (HCC), HCV has been strongly linked to metabolic disorders, particularly type 2 diabetes mellitus (T2DM).
Shen‐Shong Chang, Ching‐Hsuan Liu, Shu‐Yen Chan, Liang‐Tzung Lin   +3 more
wiley   +1 more source

Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression

Scientific Reports, 2017
In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue.
Ziqiang Teo, Jeremy Soon Kiat Chan, Han Chung Chong, Ming Keat Sng, Chee Chong Choo, Glendon Zhi Ming Phua, Daniel Jin Rong Teo, Pengcheng Zhu, Cleo Choong, Marcus Thien Chong Wong, Nguan Soon Tan   +10 more
doaj   +1 more source

Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues

Journal of Lipid Research, 2013
Chronic intermittent hypoxia (CIH) inhibits plasma lipoprotein clearance and adipose lipoprotein lipase (LPL) activity in association with upregulation of an LPL inhibitor angiopoietin-like protein 4 (Angptl4).
Qiaoling Yao, Mi-Kyung Shin, Jonathan C. Jun, Karen L. Hernandez, Neil R. Aggarwal, Jason R. Mock, Jason Gay, Luciano F. Drager, Vsevolod Y. Polotsky   +8 more
doaj   +1 more source